Evidence map›Paper›PMID 31450784›Full record

ArticleJournal of clinical medicine2019

Physical Activity Levels Are Low in Inoperable Lung Cancer: Exploratory Analyses from a Randomised Controlled Trial.

Lara Edbrooke, Catherine L Granger, Ross A Clark, Linda Denehy

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Association between physical activity and patient-reported outcome measures in patients with lung cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
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  4. Co-Designing Lung Cancer Rehabilitation Services for People Treated With Immunotherapy.Health expectations : an international journal of public participation in health care and health policy · 2026
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  8. The association between physical activity levels and quality of life in elderly lung cancer patients undergoing chemotherapy in China: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lara EdbrookeDepartment of Physiotherapy, The University of Melbourne, Melbourne VIC 3010, Australia. larae@unimelb.edu.au.ORCID 0000-0002-4149-5578
Catherine L GrangerDepartment of Physiotherapy, The University of Melbourne, Melbourne VIC 3010, Australia.ORCID 0000-0001-6169-370X
Ross A ClarkSchool of Health and Sport Sciences, University of the Sunshine Coast, Sippy Downs QLD 4556, Australia.
Linda DenehyAllied Health Department, Peter MacCallum Cancer Centre, Melbourne VIC 3000, Australia.

Funding

National Health and Medical Research Council APP1060484Victorian Cancer Agency ONJ16010
6 · The paper itself

Abstract

backgroundIn inoperable lung cancer, evidence is limited regarding physical activity (PA) and associations with other outcomes.

aimsin the usual care (UC) group of an RCT to (1) explore whether baseline PA was associated with improved follow-up outcomes, (2) identify baseline variables associated with higher follow-up PA and in all RCT participants, to (3) analyse patterns of objectively measured PA, and (4) report on characteristics of those who were able to maintain or increase PA levels.

methodsexploratory analyses of an assessor-blinded RCT. Outcomes, assessed at baseline, nine weeks and six months, included PA (seven-days of accelerometry), six-minute walk distance (6MWD), muscle strength, symptoms, mood and health-related quality of life (HRQoL).

results92 participants were randomised, 80 completed baseline accelerometry (39 intervention group (IG), 41 UC), characteristics: mean (SD) age 63.0 (12.3) years, 56% male, 51% stage IV disease. Baseline PA: median (IQR) steps/day 2859.6 (2034.0-3849.2) IG versus 3195.2 (2161.2-4839.0) UC. Associations between baseline PA and six-month outcomes were significant for HRQoL and 6MWD. PA at six months was significantly associated with baseline age, 6MWD and quadriceps strength. Between-group change score (steps/day) mean differences (95% CI) at nine weeks (174.5 (-1504.7 to 1853.7),

conclusionsfurther research is required to determine patient subgroups deriving the greatest benefits from PA interventions.

Indexed as

exerciselung cancerphysical activityquality of lifesymptoms

Identifiers

PMID31450784
PMCPMC6780073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.