Evidence map›Paper›PMID 31450762›Full record

ArticlePharmaceutics2019

Folic Acid and PEI Modified Mesoporous Silica for Targeted Delivery of Curcumin.

Xiaoxiao Sun, Nan Wang, Li-Ye Yang, Xiao-Kun Ouyang, Fangfang Huang

Erratum issuedAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Xiaoxiao SunSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Nan WangSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Li-Ye YangSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Xiao-Kun OuyangSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China. xkouyang@zjou.edu.cn.ORCID 0000-0002-8534-0279
Fangfang HuangSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.

Funding

Bureau of Science and Technology of Zhoushan 2019C21023National Natural Science Foundation of China 21476212Science and Technology Department of Zhejiang Province 2018C02038
6 · The paper itself

Abstract

Nano anti-cancer drug carriers loaded with antineoplastic drugs can achieve targeted drug delivery, which enriches drugs at tumor sites and reduces the toxic side effects in normal tissues. Mesoporous silica nanoparticles (MSN) are good nano drug carriers, as they have large specific surface areas, adjustable pore sizes, easily modifiable surfaces, and good biocompatibility. In this work, polyethyleneimine (PEI) grafted MSN were modified with folic acid (FA) as an active target molecule using chemical methods. The product was characterized by SEM, TEM, Zetasizer nano, FTIR, and an N

Indexed as

cancercurcumindeliveryfunctionalmesoporous silica nanoparticles

Identifiers

PMID31450762
PMCPMC6781278

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.