ReviewMicroorganisms2019
Does Soil Contribute to the Human Gut Microbiome?
Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07742319 (The Effect of Soil Biodiversity on Human Gut Microbiome), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Soil Biodiversity on Human Gut Microbiome: a Process Pilot Study (The HUMANITAS Study)
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Microbiome and One Health in GCC countries: current status, research gaps, and future directions.Frontiers in microbiology · 2026Pooled it
- InferiorMicrobial genomics · 2024Pooled it
- Supplemental Nutrition Assistance Program-Education (SNAP-Ed) Supporting Innovative Nutrition Education for American Indian and Indigenous-Serving Organizations in Colorado.Current developments in nutrition · 2026Article
- The Gut Microbiome of the Goitered Gazelle Enables Plasticity by Responding to Environmental Factors in the Qaidam Basin.Biology · 2026Article
- The ethnicity and gut microbiota hypothesis: analyzing multifactorial interactions and their health implications.Frontiers in microbiology · 2026Review
- Ignoring the planet: A critical blind spot for research on ageing.Journal of internal medicine · 2025Review
- Relationship of the Landscape Configuration with the Gut Parasites and Fungi Diversity in Farm Animals Associated with Conservation Areas in Colombia: Epidemiological Risk to Wildlife.Acta parasitologica · 2025Article
- Revealing the spatial heterogeneity of the gut microbiota of red-feather ducks and their interaction with environmental microorganisms.Poultry science · 2025Article
- The soil-plant-human gut microbiome axis into perspective.Nature communications · 2025Review
- Influence of Two Root Media and Three Vermicompost Amendments on Bacterial Communities in a Greenhouse Container Garden Model System.Microorganisms · 2025Article
- Tricky with Heat and Salt: Soil Factors, Thermotaxis, and Potential for Heat-Saline Agar Trapping ofBiology · 2025Article
- Addressing Antimicrobial Resistance by Changing Our Relationships with Microbes: Lessons from Japan.Delaware journal of public health · 2025Article
- Human Milk Microbiome from Polish Women Giving Birth via Vaginal Delivery-Pilot Study.Biology · 2025Article
- Harnessing Evolution and Biomimetics to Enhance Planetary Health: Kidney Insights.Journal of the American Society of Nephrology : JASN · 2025Review
- Growth promotion and stress tolerance of soybean plants driven by seed treatment with synthetic bacterial community of soybean-associated beneficial bacteria.Frontiers in plant science · 2025Article
- A microbial symphony: a literature review of the factors that orchestrate the colonization dynamics of the human colonic microbiome during infancy and implications for future health.Microbiome research reports · 2025Review
- The United European Gastroenterology green paper-climate change and gastroenterology.United European gastroenterology journal · 2024Review
- Impact of urbanization on gut microbiome mosaics across geographic and dietary contexts.mSystems · 2024Article
- Article
- Targeted viromes and total metagenomes capture distinct components of bee gut phage communities.Microbiome · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soil and the human gut contain approximately the same number of active microorganisms, while human gut microbiome diversity is only 10% that of soil biodiversity and has decreased dramatically with the modern lifestyle. We tracked relationships between the soil microbiome and the human intestinal microbiome. We propose a novel environmental microbiome hypothesis, which implies that a close linkage between the soil microbiome and the human intestinal microbiome has evolved during evolution and is still developing. From hunter-gatherers to an urbanized society, the human gut has lost alpha diversity. Interestingly, beta diversity has increased, meaning that people in urban areas have more differentiated individual microbiomes. On top of little contact with soil and feces, hygienic measures, antibiotics and a low fiber diet of processed food have led to a loss of beneficial microbes. At the same time, loss of soil biodiversity is observed in many rural areas. The increasing use of agrochemicals, low plant biodiversity and rigorous soil management practices have a negative effect on the biodiversity of crop epiphytes and endophytes. These developments concur with an increase in lifestyle diseases related to the human intestinal microbiome. We point out the interference with the microbial cycle of urban human environments versus pre-industrial rural environments. In order to correct these interferences, it may be useful to adopt a different perspective and to consider the human intestinal microbiome as well as the soil/root microbiome as 'superorganisms' which, by close contact, replenish each other with inoculants, genes and growth-sustaining molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.