Evidence map›Paper›PMID 31450696›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis of Novel 2-(Het)arylpyrrolidine Derivatives and Evaluation of Their Anticancer and Anti-Biofilm Activity.

Andrey Smolobochkin, Almir Gazizov, Marina Sazykina, Nurgali Akylbekov, Elena Chugunova, Ivan Sazykin, Anastasiya Gildebrant, Julia Voronina, Alexander Burilov, Shorena Karchava and 8 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Molecular design and synthesis of methoxy-substitued spiropyrans with photomodulated NIR-fluorescence.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Andrey SmolobochkinArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str., 8, Kazan 420088, Russia.ORCID 0000-0002-1470-8136
Almir GazizovArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str., 8, Kazan 420088, Russia. agazizov@iopc.ru.ORCID 0000-0001-9899-9606
Marina SazykinaSouthern Federal University, Stachki Avenue, 194/2, Rostov-on-Don 344090, Russia.ORCID 0000-0001-6974-3361
Nurgali AkylbekovInstitute of Chemical Research and Technology of Korkyt Ata Kyzylorda State University, Aiteke bie str., 29A, Kyzylorda 120014, Kazakhstan.
Elena ChugunovaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str., 8, Kazan 420088, Russia. chugunova.e.a@gmail.com.ORCID 0000-0002-9371-1877
Ivan SazykinSouthern Federal University, Stachki Avenue, 194/2, Rostov-on-Don 344090, Russia.
Anastasiya GildebrantSouthern Federal University, Stachki Avenue, 194/2, Rostov-on-Don 344090, Russia.ORCID 0000-0001-9308-2022
Julia VoroninaN. S. Kurnakov Institute of General and Inorganic Chemistry, RAS, 31 Leninsky Av., Moscow 119991, Russia.
Alexander BurilovArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str., 8, Kazan 420088, Russia.
Shorena KarchavaSouthern Federal University, Stachki Avenue, 194/2, Rostov-on-Don 344090, Russia.ORCID 0000-0003-3617-1904
Maria KlimovaSouthern Federal University, Stachki Avenue, 194/2, Rostov-on-Don 344090, Russia.
Alexandra VoloshinaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str., 8, Kazan 420088, Russia.
Anastasia SapunovaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str., 8, Kazan 420088, Russia.
Elena KlimanovaInstitute of Problems of Chemical Physics RAS, Chernogolovka 142432, Russia.
Tatyana SashenkovaInstitute of Problems of Chemical Physics RAS, Chernogolovka 142432, Russia.
Ugulzhan AllayarovaInstitute of Problems of Chemical Physics RAS, Chernogolovka 142432, Russia.
Anastasiya BalakinaInstitute of Problems of Chemical Physics RAS, Chernogolovka 142432, Russia.
Denis MishchenkoInstitute of Problems of Chemical Physics RAS, Chernogolovka 142432, Russia.ORCID 0000-0003-3779-3211
A.E. Arbuzov Institute of Organic and Physical Chemistry · RUSouthern Federal University · RUInstitute of Problems of Chemical Physics · RUMoscow Region State University · RUKazan Federal University · RUKorkyt Ata Kyzylorda State University · KZNS Kurnakova Institute of General and Inorganic Chemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A library of novel 2-(het)arylpyrrolidine-1-carboxamides were obtained via a modular approach based on the intramolecular cyclization/Mannich-type reaction of

Indexed as

AnimalsAnti-Infective AgentsAntineoplastic AgentsBiofilmsCell Line, TumorChemistry Techniques, SyntheticDose-Response Relationship, DrugHumansMiceMicrobial Sensitivity TestsModels, MolecularMolecular ConformationMolecular StructurePyrrolidinesStructure-Activity RelationshipAnti-Infective AgentsAntineoplastic AgentspyrrolidinePyrrolidinesanti-bacterial activityanti-cancer activityanti-tumor activityapoptosisbacterial biofilmcarboxamidecytotoxicitypyrrolidine

Identifiers

PMID31450696
PMCPMC6749236
OpenAlexW2969473962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.