Evidence map›Paper›PMID 31450655›Full record

ReviewMedicina (Kaunas, Lithuania)2019

Systemic Mastocytosis and Essential Thrombocythemia: Case Report and Literature Overview.

Mauro Cancian, Elisabetta Cosi, Marco Pizzi, Sandro Giannini, Irene Bertozzi, Fabrizio Fabris, Maria Luigia Randi

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Biconcave vertebral fractures as a possible distinctive feature of indolent systemic mastocytosis compared with primary osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mauro CancianFirst Medical Clinic, Department of Medicine, University of Padova, I-35128 Padova, Italy. mcancian@unipd.it.ORCID 0000-0003-2246-9144
Elisabetta CosiFirst Medical Clinic, Department of Medicine, University of Padova, I-35128 Padova, Italy.
Marco PizziSurgical Pathology and Cytopathology Unit, Department of Medicine, University of Padova, I-35128 Padova, Italy.
Sandro GianniniFirst Medical Clinic, Department of Medicine, University of Padova, I-35128 Padova, Italy.
Irene BertozziFirst Medical Clinic, Department of Medicine, University of Padova, I-35128 Padova, Italy.
Fabrizio FabrisFirst Medical Clinic, Department of Medicine, University of Padova, I-35128 Padova, Italy.
Maria Luigia RandiFirst Medical Clinic, Department of Medicine, University of Padova, I-35128 Padova, Italy.ORCID 0000-0001-7945-1864
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastocytosis is a rare disease in which heightened amounts of mast cells accumulate in the skin, bone marrow, and other visceral organs. Upon activation, mast cells release a wide variety of preformed or newly synthesized mediators which can induce allergic symptoms and inflammatory reactions. Mastocytosis is diagnosed by biopsy and can be divided into cutaneous and systemic mastocytosis (SM). The first one affects the skin and is relatively benign, whilst SM, which involves bone marrow and other organs, may be aggressive and associate with both myelodisplastic and myeloproliferative diseases. Here we present a case of SM associated with essential thrombocythemia and complicated by severe osteoporosis, successfully treated with hydroxyurea, low-dose aspirin and zolendronic acid.

Indexed as

BiopsyBone MarrowHumansMaleMastocytosis, SystemicMiddle AgedThrombocytosishydroxyureamastocytosisosteoporosisthrombocythemiazolendronic acid

Identifiers

PMID31450655
PMCPMC6780398
OpenAlexW2969753153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.