Evidence map›Paper›PMID 31450647›Full record

ReviewInternational journal of molecular sciences2019

Molecular-Level Interactions between Engineered Materials and Cells.

Yoon-Ha Jang, Xuelin Jin, Prabakaran Shankar, Jung Heon Lee, Kyubong Jo, Kwang-Il Lim

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoon-Ha JangDepartment of Chemical and Biological Engineering, Sookmyung Women's University, Seoul 04310, Korea.
Xuelin JinDepartment of Chemistry and Integrated Biotechnology, Sogang University, Seoul 04107, Korea.
Prabakaran ShankarSchool of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Korea.ORCID 0000-0002-2954-324X
Jung Heon LeeSchool of Advanced Materials Science and Engineering, Sungkyunkwan University (SKKU), Suwon 16419, Korea. jhlee7@skku.edu.ORCID 0000-0003-4790-3525
Kyubong JoDepartment of Chemistry and Integrated Biotechnology, Sogang University, Seoul 04107, Korea. jokyubong@sogang.ac.kr.ORCID 0000-0002-5551-8195
Kwang-Il LimDepartment of Chemical and Biological Engineering, Sookmyung Women's University, Seoul 04310, Korea. klim@sookmyung.ac.kr.

Funding

MAFRA 118094-03National Research Foundation of Korea NRF2016M3A9B6947831
6 · The paper itself

Abstract

Various recent experimental observations indicate that growing cells on engineered materials can alter their physiology, function, and fate. This finding suggests that better molecular-level understanding of the interactions between cells and materials may guide the design and construction of sophisticated artificial substrates, potentially enabling control of cells for use in various biomedical applications. In this review, we introduce recent research results that shed light on molecular events and mechanisms involved in the interactions between cells and materials. We discuss the development of materials with distinct physical, chemical, and biological features, cellular sensing of the engineered materials, transfer of the sensing information to the cell nucleus, subsequent changes in physical and chemical states of genomic DNA, and finally the resulting cellular behavior changes. Ongoing efforts to advance materials engineering and the cell-material interface will eventually expand the cell-based applications in therapies and tissue regenerations.

Indexed as

Biocompatible MaterialsCell SurvivalTissue EngineeringTissue ScaffoldsAnimalsBiophysical PhenomenaCell Culture TechniquesChemical PhenomenaGene ExpressionHumansMechanotransduction, CellularBiocompatible Materialscell surface sensorscellular responsesgenome statesmaterials engineeringmechanotransduction

Identifiers

PMID31450647
PMCPMC6747072

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.