ReviewGenes2019
Integration of Bioinformatic Predictions and Experimental Data to Identify circRNA-miRNA Associations.
Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed.
- Circular RNA circ_0003423 Promotes Osteoarthritis Progression by Sponging miR-330-5p to Upregulate TWIST1-Mediated Chondrocyte Inflammation and Extracellular Matrix Degradation.Journal of cellular and molecular medicine · 2026Article
- CircRNAs in Immuno-Metabolic Reprogramming of Chordoma Cancer: Molecular Crosstalk and Therapeutic Potential.International journal of molecular sciences · 2026Review
- DAMFCMI: capturing cross-view interactions via hybrid attention for circRNA-MiRNA interaction prediction.Bioinformatics advances · 2026Article
- Metabolic reprogramming and lung cancer focused on roles, mechanism, and clinical prospects of circRNAs: a narrative review.Frontiers in oncology · 2026Review
- circRNA_Atp8a1 Promotes Glycolytic Reprogramming in Damage of Intestinal Mucosal Barrier by Upregulating IGF2 through miR-200b-3p.Tissue engineering and regenerative medicine · 2025Article
- Therapeutic Potential of Circular RNAs as Targets for Cancer Treatment.Advanced pharmaceutical bulletin · 2025Review
- Tumor-associated macrophages derived exosomal circPLK1 promotes resistance to EGFR inhibitor osimertinib in non-small cell lung cancer.Discover oncology · 2025Article
- Role of Circular RNAs in Prostate Cancer.Current medicinal chemistry · 2024Review
- Circ_0084188 promotes colorectal cancer progression by sponging miR-654-3p and regulating kruppel-like factor 12.The Kaohsiung journal of medical sciences · 2023Article
- Circ_0084188 Regulates the progression of colorectal cancer through the miR-769-5p/KIF20A axis.Biochemical genetics · 2023Article
- Circular RNA regulation and function in drug seeking phenotypes.Molecular and cellular neurosciences · 2023Review
- Computational approaches for circRNAs prediction and in silico characterization.Briefings in bioinformatics · 2023Review
- Circ_0005615 restrains the progression of multiple myeloma through modulating miR-331-3p and IGF1R regulatory cascade.Journal of orthopaedic surgery and research · 2023Article
- Circ-Bnc2 alleviates neuroinflammation in LPS-stimulated microglial cells to inhibit neuron cell apoptosis through regulating miR-497a-5p/HECTD1 axis.Brain and behavior · 2023Article
- Circular RNA circ_SKA3 enhances gastric cancer development by targeting miR-520h.Histology and histopathology · 2023Article
- Curcumin suppresses lung cancer progression via circRUNX1 mediated miR-760/RAB3D axis.Thoracic cancer · 2023Article
- Transcriptome RNA Sequencing Reveals That Circular RNAs Are Abundantly Expressed in Embryonic Breast Muscle of Duck.Veterinary sciences · 2023Article
- Age-related ceRNA networks in adultFrontiers in genetics · 2023Article
- Circ_0083964 knockdown impedes rheumatoid arthritis progression via the miR-204-5p-dependent regulation of YY1.Journal of orthopaedic surgery and research · 2022Article
- Exosome-transmitted circVMP1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting miR-524-5p-METTL3/SOX2 axis.Drug delivery · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circular RNAs (circRNAs) have recently emerged as a novel class of transcripts, characterized by covalently linked 3'-5' ends that result in the so-called backsplice junction. During the last few years, thousands of circRNAs have been identified in different organisms. Yet, despite their role as disease biomarker started to emerge, depicting their function remains challenging. Different studies have shown that certain circRNAs act as miRNA sponges, but any attempt to generalize from the single case to the "circ-ome" has failed so far. In this review, we explore the potential to define miRNA "sponging" as a more general function of circRNAs and describe the different approaches to predict miRNA response elements (MREs) in known or novel circRNA sequences. Moreover, we discuss how experiments based on Ago2-IP and experimentally validated miRNA:target duplexes can be used to either prioritize or validate putative miRNA-circRNA associations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.