Evidence map›Paper›PMID 31450563›Full record

Trial reportNutrients2019

Tolerability and Safety of a Nutritional Supplement with Potential as Adjuvant in Colorectal Cancer Therapy: A Randomized Trial in Healthy Volunteers.

Marta Gómez de Cedrón, José Moises Laparra, Viviana Loria-Kohen, Susana Molina, Juan Moreno-Rubio, Juan Jose Montoya, Carlos Torres, Enrique Casado, Guillermo Reglero, Ana Ramírez de Molina

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05080920 (A Pilot, Randomized, Double Blind, Placebo Controlled Study to Evaluate an Immune System Modulator Nutritional Supplement for the Prevention of Infections in Cancer Patients Receiving Oncologic Treatment During the COVID-19 Pandemia.), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05080920 nacompletednot on this mapstarted 2020, after this paper: background citation

A Pilot, Randomized, Double Blind, Placebo Controlled Study to Evaluate an Immune System Modulator Nutritional Supplement for the Prevention of Infections in Cancer Patients Receiving Oncologic Treatment During the COVID-19 Pandemia.

TypeinterventionalSponsorFundación Investigación E Innovación Biomédica Hospital Universitario Infanta Sofia-HenaresRan2020 to 2022Enrolled109ConditionsInfections, Covid19, CancerArmsRosmalip®, Placebo
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Anticancer Activity ofNutrients · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marta Gómez de CedrónMolecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid 28049, Spain. marta.gomezdecedron@imdea.org.ORCID 0000-0002-0894-970X
José Moises LaparraMolecular Immuno-Nutrition Group, IMDEA-Food Institute, CEI UAM+CSIC, Madrid 28049, Spain.
Viviana Loria-KohenNutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute, CEI UAM + CSIC, Madrid 28049, Spain.ORCID 0000-0001-8686-3306
Susana MolinaMolecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid 28049, Spain.
Juan Moreno-RubioMolecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid 28049, Spain.
Juan Jose MontoyaDerma Innovate, Faculty of Medicine, Complutense University, Madrid 28040, Spain.
Carlos TorresProduction and Characterization of Novel Foods, CIAL, CEI UAM+CSIC, Madrid 28049, Spain.
Enrique CasadoPrecision Oncology Laboratory (POL), Infanta Sofía University Hospital, Madrid 28702, Spain.
Guillermo RegleroProduction and Characterization of Novel Foods, CIAL, CEI UAM+CSIC, Madrid 28049, Spain.
Ana Ramírez de MolinaMolecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, Madrid 28049, Spain. ana.ramirez@imdea.org.
Madrid Institute for Advanced Studies · ESHospital Universitario Infanta Sofía · ESInstituto de Investigación en Ciencias de la Alimentación · ESUniversidad Complutense de Madrid · ES

Funding

ENDORPHINS: TOLERANCE AND DEPENDENCER01DA002013 · NIDA · NEW YORK UNIVERSITY · PI MUSACCHIO, JOSE M · 1986 to 1988
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Comunidad de Madrid Government Project P2013/ABI-2728, ALIBIRD-CMEU Structural Funds EU Structural FundsMinisterio de Economía y Competitividad Spain Government MINECO, Project I+D+i AGL2016-76736-C3
6 · The paper itself

Abstract

Bioactive supplements display relevant therapeutic properties when properly applied according to validated molecular effects. Our previous research efforts established the basis to develop a dietary supplement based on a

Indexed as

Dietary SupplementsSharksAdolescentAdultAnimalsCell Line, TumorColorectal NeoplasmsDouble-Blind MethodFemaleFish OilsHealthy VolunteersHumansLeukocytesLiverMalePatient SafetyFish OilsPlant Extractsalkylglycerolscolon cancerimmuno-nutritionRosmarinus officinalis L.

Identifiers

PMID31450563
PMCPMC6769991
OpenAlexW2969998176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.