Evidence map›Paper›PMID 31450549›Full record

ArticleMarine drugs2019

A Quorum-Sensing Inhibitor Strain of

José Carlos Reina, Ignacio Pérez-Victoria, Jesús Martín, Inmaculada Llamas

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Biogenic Quorum-Sensing Amides fromMolecules (Basel, Switzerland) · 2026
    Article
  4. Antimicrobial Compounds FromInternational journal of microbiology · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. The Molecular Architecture ofMarine drugs · 2022
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. PeerJ · 2021
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

José Carlos ReinaDepartment of Microbiology, Faculty of Pharmacy, University of Granada, Campus Universitario Cartuja s/n, 18071 Granada, Spain.ORCID 0000-0002-6418-9805
Ignacio Pérez-VictoriaMEDINA Foundation, Andalusian Center of Excellence for Research into Innovative Medicines, Health Sciences Technological Park (PTS), Avda. del Conocimiento 34, 18016 Armilla, Granada, Spain. ignacio.perez-victoria@medinaandalucia.es.
Jesús MartínMEDINA Foundation, Andalusian Center of Excellence for Research into Innovative Medicines, Health Sciences Technological Park (PTS), Avda. del Conocimiento 34, 18016 Armilla, Granada, Spain.
Inmaculada LlamasDepartment of Microbiology, Faculty of Pharmacy, University of Granada, Campus Universitario Cartuja s/n, 18071 Granada, Spain. illamas@ugr.es.ORCID 0000-0002-4556-688X
Fundación Medina · ESUniversidad de Granada · ES

Funding

Ministerio de Economía y Competitividad AGL2015-68806-R
6 · The paper itself

Abstract

The cell density-dependent mechanism, quorum sensing (QS), regulates the expression of virulence factors. Its inhibition has been proposed as a promising new strategy to prevent bacterial pathogenicity. In this study, 827 strains from the microbiota of sea anemones and holothurians were screened for their ability to produce quorum-sensing inhibitor (QSI) compounds. The strain M3-10, identified as

Indexed as

AnimalsAnti-Bacterial AgentsBiofilmsChromobacteriumIndolesMicrobiotaPseudomonas aeruginosaQuorum SensingSea AnemonesTyramineVibrio alginolyticusVirulence FactorsAnti-Bacterial AgentsIndolesN-acetyltyramineTyramineviolaceinVirulence FactorsaquacultureLC–MSmarine bacteriaN-acetyltyramineNMRquorum sensing inhibitortyramine

Identifiers

PMID31450549
PMCPMC6780304
OpenAlexW2969920240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.