Evidence map›Paper›PMID 31449745›Full record

ArticleJournal of the American Chemical Society2019

Luo-Yan Liu, Jennifer X Qiao, Kap-Sun Yeung, William R Ewing, Jin-Quan Yu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Ligand-Controlled NondirectedACS catalysis · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Site-Selective C-H Arylation of Diverse Arenes Ortho to Small Alkyl Groups.Angewandte Chemie (International ed. in English) · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. meta-Selective C-H Arylation of Fluoroarenes and Simple Arenes.Angewandte Chemie (International ed. in English) · 2020
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luo-Yan LiuDepartment of Chemistry , The Scripps Research Institute , 10550 N. Torrey Pines Road , La Jolla , California 92037 , United States.
Jennifer X QiaoDiscovery Chemistry , Bristol-Myers Squibb , PO Box 4000, Princeton , New Jersey 08543 , United States.
Kap-Sun YeungDiscovery Chemistry , Bristol-Myers Squibb Research and Development , 100 Binney Street , Cambridge , Massachusetts 02142 , United States.ORCID 0000-0003-3995-6555
William R EwingDiscovery Chemistry , Bristol-Myers Squibb , PO Box 4000, Princeton , New Jersey 08543 , United States.
Jin-Quan YuDepartment of Chemistry , The Scripps Research Institute , 10550 N. Torrey Pines Road , La Jolla , California 92037 , United States.ORCID 0000-0003-3560-5774

Funding

Catalyst-Controlled Site-Selective C-H Functionalizations of Arenes and HeteroarenesR01GM102265 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2012 to 2023
$4.6M
NIGMS NIH HHS R01 GM102265
6 · The paper itself

Abstract

Controlling site selectivity of C-H activation without using a directing group remains a significant challenge. While Pd(II) catalysts modulated by a mutually repulsive pyridine-type ligand have been shown to favor the relatively electron-rich carbon centers of arenes, reversing the selectivity to favor palladation at the relatively electron-deficient positions has not been possible. Herein we report the first catalytic system that effectively performs

Indexed as

CatalysisChromansDibenzofuransElectronsHydrocarbonsLigandsPalladiumChromansDibenzofuransHydrocarbonsLigandsPalladium

Identifiers

PMID31449745
PMCPMC6750962

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.