ArticlePloS one2019
What works best for ensuring treatment adherence. Lessons from a social support program for people treated for tuberculosis in Ukraine.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- "They hide because they fear": Barriers and opportunities for tuberculosis control in rural Indonesia through the PRECEDE-PROCEED lens.Journal of public health research · 2026Article
- Culturally Responsive Counseling and Tuberculosis Treatment Adherence: Development and Validation of an Integrated Model.Nursing reports (Pavia, Italy) · 2026Article
- The Feasibility of Implementing Interprofessional Collaboration-Based Telecare Services for Patients With Tuberculosis: A Mixed Methods Study From Hospital Insight.Interdisciplinary perspectives on infectious diseases · 2026Article
- WHO's end of TB targets: unachievable by 2035 without addressing under nutrition, forced displacement, and homelessness: trend analysis from 2015 to 2022.BMC public health · 2024Article
- Psychosocial support interventions to improve treatment outcomes for people living with tuberculosis: a mixed methods systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections.Scientific reports · 2021Article
- Acceptability, feasibility, and likelihood of stakeholders implementing the novel BPaL regimen to treat extensively drug-resistant tuberculosis patients.BMC public health · 2021Article
- Patients' perspectives of tuberculosis treatment challenges and barriers to treatment adherence in Ukraine: a qualitative study.BMJ open · 2020Article
- Tuberculosis Treatment Adherence as a Relational and Cultural Process: A Qualitative Study From Urban Indonesia.Global qualitative nursing researchArticle
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Abstract
backgroundWorldwide, TB is one of the top 10 causes of death and the leading cause from a single infectious agent. Ukraine is one of 30 countries with the highest burden of multidrug-resistant tuberculosis. Global literature shows that social support (SS) is important in improving TB treatment adherence, reducing lost to follow up rates and improving treatment outcomes. There are several models of SS available, and the literature provides little information on what aspects of SS are most important to TB patients in improving their adherence.
methodsWe used qualitative data collected through in-depth interviews (IDI) with 21 TB patients and 15 SS providers and coordinators in Ukraine in August-September 2016 to understand how the SS program promoted treatment adherence among patients. We examined the aspects of outpatient TB treatment that made adherence particularly difficult for patients in at-risk groups and aspects of the SS programs that worked best for addressing those barriers. Interviews were transcribed and analysis was performed to derive emergent themes.
resultsMain barriers included side effects from medicine, the amount of time required daily for transportation and waiting in lines at the health facility, transportation expenses, risks of being identified when visiting a TB facility and lack of motivation to seek treatment. Features of the SS program most valued by patients were convenience of not having to visit facility and support provided by nurses. These two features directly addressed most of the barriers identified. The commitment and qualities of the nurses that provided the SS was an important element of the program.
conclusionsThis qualitative study suggests that the SS program in Ukraine was successful in reducing treatment default among patients at high risk of default because it directly addressed most of the major barriers they faced to treatment adherence.
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