Evidence map›Paper›PMID 31449011›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2019

Microbubble Radiation Force-Induced Translation in Plane-Wave Versus Focused Transmission Modes.

Francesco Guidi, Outi Supponen, Awaneesh Upadhyay, Hendrik J Vos, Mark Andrew Borden, Piero Tortoli

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Francesco Guidi
Outi Supponen
Awaneesh Upadhyay
Hendrik J Vos
Mark Andrew Borden
Piero Tortoli
University of Colorado Boulder · USUniversity of Florence · ITErasmus University Rotterdam · NL

Funding

Ultrasound Molecular Imaging to Assess Therapeutic ResponseR01CA195051 · NCI · UNIVERSITY OF COLORADO · PI BORDEN, MARK ANDREW, DAYTON, PAUL A · 2015 to 2018
$2.0M
NCI NIH HHS R01 CA195051
6 · The paper itself

Abstract

Due to the primary radiation force, microbubble displacement has been observed previously in the focal region of single-element and array ultrasound probes. This effect has been harnessed to increase the contact between the microbubbles and targeted endothelium for drug delivery and ultrasound molecular imaging. In this study, microbubble displacements associated with plane-wave (PW) transmission are thoroughly investigated and compared to those obtained in focused-wave (FW) transmission over a range of pulse repetition frequencies, burst lengths (BLs), peak negative pressures, and transmission frequencies. In PW mode, the displacements, depending upon the experimental conditions, are in some cases consistently higher (e.g., by 28%, when the longest BL was used at PRF = 4 kHz), and the axial displacements are spatially more uniform compared to FW mode. Statistical analysis on the measured displacements reveals a slightly different frequency dependence of statistical quantities compared to transient peak microbubble displacements, which may suggest the need to consider the size range within the tested microbubble population.

Indexed as

MicrobubblesContrast MediaMolecular ImagingTransducersUltrasonographyContrast Media

Identifiers

PMID31449011
PMCPMC6900931
OpenAlexW2969728464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.