ReviewNeuropsychology2019
At the intersection of alcohol use disorder and chronic pain.
Review in Neuropsychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 83 citations in OpenAlex.
- Pilot RCT comparing low-dose naltrexone, gabapentin and placebo to reduce pain among people with HIV with alcohol problems.PloS one · 2024Trial
- Mobile App Engagement and Pain Outcomes Among Primary Care Chronic Pain Patients Who Engage in Hazardous Drinking: A Pilot Study.Journal of clinical psychology in medical settings · 2026Article
- The analgesic effect of neuropeptide S (NPS) in alcohol-dependent male and female rats.Alcohol (Fayetteville, N.Y.) · 2026Article
- Daily Associations Between Perceived Stress, Pain Intensity, and Alcohol Use Among Veterans With and Without Moderate-to-Severe Chronic Pain.Stress and health : journal of the International Society for the Investigation of Stress · 2026Article
- Article
- Chronic alcohol drinking delays recovery from capsaicin- and nerve injury-induced hypersensitivity in mice.Alcohol (Fayetteville, N.Y.) · 2025Article
- Pain and alcohol consumption among people living with HIV: examining the moderating roles of depression and social support.Alcohol (Fayetteville, N.Y.) · 2025Article
- Understanding the Comorbidities Among Psychiatric Disorders, Chronic Low Back Pain, and Spinal Degenerative Disease Using Observational and Genetically Informed Analyses.Biological psychiatry global open science · 2025Article
- Chronic alcohol drinking delays recovery from capsaicin- and nerve injury-induced hypersensitivity in mice.bioRxiv : the preprint server for biology · 2025Article
- VA Primary Care Patients with Chronic Pain: A Comparison of Healthcare Utilization and Patient Characteristics Across Alcohol Risk Categories.Journal of clinical psychology in medical settings · 2025Article
- Type 2 Diabetes Health Care Outcomes for Patients with Alcohol Use Disorder Starting Addiction Treatment.Journal of general internal medicine · 2025Article
- Sex differences in the transition to chronic pain.The Journal of clinical investigation · 2025Review
- Apremilast reduces co-occurring alcohol drinking and mechanical allodynia and regulates central amygdala GABAergic transmission.JCI insight · 2025Article
- Neural, Motivational, and Psychological Measures of Pain Avoidance Predict Future Alcohol Use in Adult Drinkers.Addiction biology · 2025Article
- Pain and unhealthy alcohol use among people living with HIV: A prospective cohort study.Alcohol, clinical & experimental research · 2024Article
- A neural circuit for alcohol withdrawal-induced hyperalgesia in a nondependent state.Science advances · 2024Article
- Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders.Molecular psychiatry · 2024Article
- Pain in alcohol use disorder: Evaluating effects of childhood trauma, perceived stress, and psychological comorbidity.Alcohol (Fayetteville, N.Y.) · 2024Article
- Heavy Alcohol Use and HIV Outcomes: The Moderating Role of Pain.AIDS and behavior · 2024Article
- Long-lasting mechanical hypersensitivity and CRF receptor type-1 neuron activation in the BNST following adolescent ethanol exposure.Alcohol, clinical & experimental research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveAlcohol use disorder (AUD) and chronic pain are widespread conditions with extensive public health burden. This review seeks to describe neuroanatomical links and major mediating influences between AUD and chronic pain, in the service of identifying factors that predict the risk of chronic pain in precipitating or facilitating AUD.
methodWe review the neural bases of pain and the influence of AUD on processes involved in pain perception. We propose potential mechanisms involved in the development of chronic pain in AUD, and we consider implications for pain management in recovery from AUD.
resultsPain is a multidimensional and subjective experience that, in its acute form, is essential for survival, but in chronic form, pain is a disorder that negatively impacts quality of life. Neural substrates involved in initiating and maintaining chronic pain include dysfunction in descending pain pathways and reward network circuitry. AUD involves preoccupation or craving, intoxication, withdrawal, and negative affect. Neural substrates of AUD involve widespread mesocorticolimbic and cerebrocerebellar networks. Both conditions involve dysfunction of extended reward and oversight circuitry, particularly prefrontal cortex.
conclusionsThe interrelationship between chronic pain and AUD resides in the intersection of etiological influences, mental experiences, and neurobiological processes. Characterization of the connection between brain and behavioral abnormalities in AUD's precipitation of chronic pain-and vice versa-allows for early detection and treatment of patients at risk for developing either or both of these conditions and for preemptive interventional approaches to reduce the risk of consequent vulnerabilities and harm. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.