Evidence map›Paper›PMID 31448866›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2019

The prevalence and predictors of resistant hypertension in high-risk overweight and obese patients: A cross-sectional study based on the 2017 ACC/AHA guidelines.

Faris Haddadin, Karan Sud, Alba Munoz Estrella, Sananda Moctezuma, Lingling Wu, Joshua Berookhim, Claire Huang Lucas, Dipal Patel, Edgar Argulian

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
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  7. Review
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  9. Article
  10. Obesity and resistant hypertension: Never ending story.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Faris HaddadinDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.ORCID 0000-0002-2122-3110
Karan SudDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Alba Munoz EstrellaDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Sananda MoctezumaDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Lingling WuDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Joshua BerookhimDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Claire Huang LucasDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Dipal PatelDepartment of Medicine at Mount Sinai St Luke's Hospital, New York, NY, USA.
Edgar ArgulianCardiovascular Department at Mount Sinai St Luke's Hospital, New York, NY, USA.
St. Luke's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is significantly associated with uncontrolled blood pressure and resistant hypertension (RH). There are limited studies on the prevalence and determinants of RH in patients with higher body mass index (BMI) values. Since the hypertension guidelines changed in 2017, the prevalence of RH has become unknown and now is subject to be estimated by further studies. We conducted a cross-sectional study in an urban Federally Qualified Health Center in New York City aiming to estimate the prevalence of RH in high-risk overweight and obese patients based on the new hypertension definition, BP threshold ≥130/80 mm Hg, and also to describe the associated comorbid conditions in these patients. We identified 761 eligible high-risk overweight and obese subjects with hypertension between October 2017 and October 2018. Apparent treatment-RH was found in 13.6% among the entire study population. This represented 15.4% of those treated with BP-lowering agents. True RH confirmed with out-of-office elevated BP was found in 6.7% of the study population and 7.4% among patients treated with BP-lowering agents. Prevalence was higher with higher BMI values. Those with true RH were more likely to be black, to have diabetes mellitus requiring insulin, chronic kidney disease stage 3 or above and diastolic heart failure. In conclusion, obesity is significantly associated with RH and other significant metabolic comorbid conditions.

Indexed as

Antihypertensive AgentsBlood PressureBlood Pressure DeterminationBody Mass IndexComorbidityCross-Sectional StudiesDiabetes MellitusDrug ResistanceEthnicityFemaleGuidelines as TopicHeart Failure, DiastolicHumansHypertensionInsulinMaleAntihypertensive AgentsInsulinobeseoverweightresistant hypertension

Identifiers

PMID31448866
PMCPMC8030605
OpenAlexW2970798807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.