Evidence map›Paper›PMID 31448852›Full record

ReviewClinical cardiology2019

Opportunities for improving use of evidence-based therapy in patients with type 2 diabetes and cardiovascular disease.

Yumin Gao, Eric Peterson, Neha Pagidipati

Open access · goldAbstract readReview
In one paragraph

Review in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Moving the Dial on Heart Failure Patient Adherence Rates.Patient preference and adherence · 2020
    Review
  4. Review
  5. Diabetes Today.SAGE open nursing
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yumin GaoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.ORCID https://orcid.org/0000-0001-5297-7524
Eric PetersonDepartment of Medicine, Duke Clinical Research Institute, Center for Preventive Medicine, Duke University, Durham, North Carolina.
Neha PagidipatiDepartment of Medicine, Duke Clinical Research Institute, Center for Preventive Medicine, Duke University, Durham, North Carolina.
Duke University · USJohns Hopkins University · US

Funding

Dissemination and Implementation Science in Cardiovascular Outcomes (DISCO)K12HL138030 · NHLBI · DUKE UNIVERSITY · PI BOSWORTH, HAYDEN B · 2017 to 2021
$3.9M
Alexion Pharmaceuticals, Inc.Amarin CorporationAmgen Biotechnology CompanyAmgen, Inc.Astra ZenecaBaseline Study LLCEli Lilly & CompanyGenentechJanssen PharmMerck & Co, Inc.NHLBI NIH HHS K12 HL138030Novartis Pharmaceutical CompanyReflexion HealthRegeneronRegeneron Pharmaceuticals, Inc.Sanofi-AventisSanofi S.A.Society of Thoracic SurgeonsVerily Life Sciences Research Company
6 · The paper itself

Abstract

Evidence-based therapy that target hyperlipidemia, hypertension, smoking cessation, and weight loss have demonstrated significant benefits in reducing cardiovascular risks and related events. Although the benefit of intensively lowering blood glucose is unclear, newer antidiabetic drugs (glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors) have shown cardiovascular benefits in addition to their antihyperglycemic effect. Yet, studies suggest that recent use of evidence-based therapy and management of cardiovascular risk among individuals with type 2 diabetes (T2D) and cardiovascular disease (CVD) remains largely suboptimal. The following narrative review first identifies barriers to translating research evidence to clinical practice at the levels of provider, health system, patient, and cost. Then it synthesizes previous implementation strategies that addressed multifaceted barriers and attempted to improve care for patients with T2D and CVD. In conclusion, team-based care coordination, reminding systems in combination to pharmacist consultation and patient education, provider education compatible with clinical workflow, and coupled incentives between providers and patients appeared to be effective in reducing cardiovascular risks for patients with T2D and CVD, though the scalability and long-term clinical effect of these strategies as well as the possibility of interventions involving payers and health systems remain uncertain.

Indexed as

Disease ManagementCardiovascular DiseasesDiabetes Mellitus, Type 2Evidence-Based MedicineGlobal HealthHumansHypoglycemic AgentsMorbidityRisk AssessmentRisk FactorsSecondary PreventionSurvival RateHypoglycemic Agentsbarriers to carecardiovascular diseaseimplementation sciencetype 2 diabetes

Identifiers

PMID31448852
PMCPMC6837027
OpenAlexW2970789459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.