Evidence map›Paper›PMID 31448381›Full record

ArticleTropical animal health and production2020

A cross-sectional epidemiological investigation of nontuberculous mycobacteria of public health importance in slaughter camels in Samburu County, Kenya.

Lucas Luvai A Asaava, Michael M Gicheru, Moses Mwangi, Edwin Mwangi, Ernest Juma, Ruth Moraa, Adan Halakhe, Willie Abela Githui

Abstract read
PubMed Publisher
In one paragraph

Article in Tropical animal health and production, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lucas Luvai A AsaavaDepartment of Zoological Sciences, Kenyatta University, Nairobi, P.O.Box 43844-00100, Nairobi, Kenya. asaava.lucas@ku.ac.ke.ORCID http://orcid.org/0000-0002-5493-8155
Michael M GicheruDepartment of Zoological Sciences, Kenyatta University, Nairobi, P.O.Box 43844-00100, Nairobi, Kenya.
Moses MwangiKenya Medical Research Institute (KEMRI) Center for Public Health Research (CPHR), P.O.Box 54840-00200, Kenyatta National Hospital Grounds, Nairobi, Kenya.
Edwin MwangiKenya Medical Research Institute (KEMRI) Center for Respiratory Diseases Research (CRDR), P.O. Box 54840-00200, Kenyatta National Hospital Grounds, Nairobi, Kenya.
Ernest JumaKenya Medical Research Institute (KEMRI) Center for Respiratory Diseases Research (CRDR), P.O. Box 54840-00200, Kenyatta National Hospital Grounds, Nairobi, Kenya.
Ruth MoraaKenya Medical Research Institute (KEMRI) Center for Respiratory Diseases Research (CRDR), P.O. Box 54840-00200, Kenyatta National Hospital Grounds, Nairobi, Kenya.
Adan HalakheDepartment of Zoological Sciences, Kenyatta University, Nairobi, P.O.Box 43844-00100, Nairobi, Kenya.
Willie Abela GithuiKenya Medical Research Institute (KEMRI) Center for Respiratory Diseases Research (CRDR), P.O. Box 54840-00200, Kenyatta National Hospital Grounds, Nairobi, Kenya.
Kenyatta National Hospital · KEKenyatta University · KE

Funding

National Research Fund (KENYA) NACOSTI/RCD/ST&I/7THCALL/PHD/258
6 · The paper itself

Abstract

The diagnosis of tuberculosis (TB) in camels at slaughter houses heavily relies on post mortem (PM) meat inspection to detect granulomatous lesions; however, the sensitivity of this technique is not perfect. The objective of this study was to isolate and characterize mycobacteria associated with suspect TB pathological lesions at PM. At PM, 1600 camels were examined in two county slaughterhouses. One hundred and thirty two, 8.25% (132/1600) (Binomial CI 95% 6.95-9.71%), suspect granulomatous lesions were found. Twenty seven, 1.69% (27/1600) (Binomial CI 95% 1.11-2.45%), were confirmed as acid-fast bacilli (AFB) using Ziehl-Neelsen (ZN) staining after culture. Speciation using the GenoType® Mycobacterium assay (Hain Lifesciences, Nehren, Germany) found a majority isolates to be Mycobacterium fortuitum (17), the other species identified included M. szulgai (2), M. scrofulaceum (3), M. marinum (1), M. intracellulare (1), M. gordonae (1), and 2 unidentified mycobacteria species. The types of lesions observed were nodular, caseous masses involving whole organs or cavities, and purulent masses. The highest proportion of suspect lesions were observed in the right, left bronchial lymph nodes, and the mediastinal lymph nodes (59.54%), followed by the retropharyngeal lymph nodes (12.21%), the medial lobe (10.67%), and the left lateral and quadrate lobes of the lungs (17.58%). The 6-7 age category had higher odds (OR = 2.5) of culture positivity. It was concluded that a variety of NTM species of medical importance were associated with TB lesions in the thoracic lymph nodes and lungs. There is need to unravel the public health significance of these mycobacteria.

Indexed as

CamelusAbattoirsAnimalsCross-Sectional StudiesFemaleKenyaMaleMycobacterium Infections, NontuberculousNontuberculous MycobacteriaPrevalencePublic HealthCamelsCultureMeat inspectionZoonotic mycobacteria

Identifiers

PMID31448381
OpenAlexW2970088239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.