Evidence map›Paper›PMID 31448295›Full record

ArticleFrontiers in veterinary science2019

D-Dimer Concentrations and Thromboelastography in Five Dogs With Ischemic Stroke.

Bodil Cathrine Koch, Luca Motta, Bo Wiinberg, Ulrik Westrup, Annemarie Thuri Kristensen, Geoff Skerritt, Mette Berendt, Hanne Gredal

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in veterinary science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Common Neurologic Diseases in Geriatric Dogs.Animals : an open access journal from MDPI · 2024
    Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Bodil Cathrine KochDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, University Hospital for Companion Animals, Frederiksberg, Denmark.
Luca MottaChesterGates Veterinary Specialists, Chester, United Kingdom.
Bo WiinbergNovo Nordisk A/S, Måløv, Denmark.
Ulrik WestrupDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, University Hospital for Companion Animals, Frederiksberg, Denmark.
Annemarie Thuri KristensenDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, University Hospital for Companion Animals, Frederiksberg, Denmark.
Geoff SkerrittChesterGates Veterinary Specialists, Chester, United Kingdom.
Mette BerendtDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, University Hospital for Companion Animals, Frederiksberg, Denmark.
Hanne GredalDepartment of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, University Hospital for Companion Animals, Frederiksberg, Denmark.
Copenhagen University Hospital · DKUniversity of Copenhagen · DKWillows Veterinary Centre and Referral Service · GBNovo Nordisk (Denmark) · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke is a condition increasingly recognized in dogs; however, the number of publications on dogs with ischemic stroke is still limited and hemostatic parameters are infrequently reported. D-dimer levels have been shown to be elevated in people with acute ischemic stroke compared to a healthy control population and it has been proposed that a normal D-dimer can be used to exclude thromboembolism in dogs. In this case series, we report hemostatic parameters, including D-dimer and thromboelastography (TEG) along with clinical and imaging findings for five dogs diagnosed with ischemic stroke. All dogs had a normal D-dimer concentration on presentation. A hypercoagulable state was identified in two dogs based on the results of the TEG, and was suspected in the remaining three cases based on a shortened TEG clot reaction time. Based on the findings in the present cases, a D-dimer within the normal reference range does not seem an appropriate negative predictor for canine ischemic stroke. The demonstration of a possible hypercoagulable state, as identified by the TEG, is an interesting finding which should be explored further to help reveal predisposing hypercoagulable conditions in dogs with ischemic stroke.

Indexed as

cerebrovascular accidentD-dimerhemostatic parametershypercoagulabilityinfarctionischemic strokeTEGthromboelastography

Identifiers

PMID31448295
PMCPMC6691767
OpenAlexW2960176814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.