Evidence map›Paper›PMID 31448131›Full record

ArticleNature reviews. Materials2017

Neural Recording and Modulation Technologies.

Ritchie Chen, Andres Canales, Polina Anikeeva

Abstract read
In one paragraph

Article in Nature reviews. Materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 230 papers.

0numbers the graph read from it
0cells of the map it votes in
230citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

230 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Shallow recurrent decoders for neural and behavioural dynamics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Article
  5. Article
  6. Review
  7. Tissue-bioelectronics interfaces.Chemical Society reviews · 2026
    Review
  8. Review
  9. An exceptionally conductive hydrogel for all-organic, ultraflexible, and chronic neural interfaces.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Article
  12. Ultrasensitive measurement of brain penetration mechanics and blood vessel rupture with microscale probes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Mechanomedicine.Nature reviews bioengineering · 2026
    Article
  18. Article
  19. Article
  20. Article

170 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ritchie ChenDepartment of Materials Science and Engineering, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Andres CanalesDepartment of Materials Science and Engineering, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Polina AnikeevaDepartment of Materials Science and Engineering, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA.

Funding

Fiber Inspired Neural Probes for the Multifunctional Dynamic Brain MappingR01NS086804 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANIKEEVA, POLINA O · 2015 to 2019
$1.7M
NINDS NIH HHS R01 NS086804
6 · The paper itself

Abstract

Within the mammalian nervous system, billions of neurons connected by quadrillions of synapses exchange electrical, chemical and mechanical signals. Disruptions to this network manifest as neurological or psychiatric conditions. Despite decades of neuroscience research, our ability to treat or even to understand these conditions is limited by the tools capable of probing the signalling complexity of the nervous system. Although orders of magnitude smaller and computationally faster than neurons, conventional substrate-bound electronics do not address the chemical and mechanical properties of neural tissue. This mismatch results in a foreign-body response and the encapsulation of devices by glial scars, suggesting that the design of an interface between the nervous system and a synthetic sensor requires additional materials innovation. Advances in genetic tools for manipulating neural activity have fuelled the demand for devices capable of simultaneous recording and controlling individual neurons at unprecedented scales. Recently, flexible organic electronics and bio- and nanomaterials have been developed for multifunctional and minimally invasive probes for long-term interaction with the nervous system. In this Review, we discuss the design lessons from the quarter-century-old field of neural engineering, highlight recent materials-driven progress in neural probes, and look at emergent directions inspired by the principles of neural transduction.

Identifiers

PMID31448131
PMCPMC6707077

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.