Evidence map›Paper›PMID 31446815›Full record

ArticlePharmaceutical biology2019

Comparison of the TLR4/NFκB and NLRP3 signalling pathways in major organs of the mouse after intravenous injection of lipopolysaccharide.

Qin Gong, Luling He, Mulan Wang, Shasha Zuo, Hongwei Gao, Yulin Feng, Lijun Du, Yingying Luo, Jun Li

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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  11. Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qin GongSchool of Pharmaceutical Sciences, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Luling HeState Key Laboratory of Innovative Drugs and Efficient Energy-saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Mulan WangState Key Laboratory of Innovative Drugs and Efficient Energy-saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Shasha ZuoState Key Laboratory of Innovative Drugs and Efficient Energy-saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Hongwei GaoCollege of Pharmacy, Guangxi University of Chinese Medicine , Nanning , China.
Yulin FengSchool of Pharmaceutical Sciences, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Lijun DuState Key Laboratory of Innovative Drugs and Efficient Energy-saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Yingying LuoSchool of Pharmaceutical Sciences, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Jun LiSchool of Pharmaceutical Sciences, Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Jiangxi University of Traditional Chinese Medicine · CNGuangxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiomarkersInflammationInjections, IntravenousIntestinesKidneyLipopolysaccharidesLiverMaleMiceMice, Inbred ICRNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinSignal TransductionToll-Like Receptor 4BiomarkersLipopolysaccharidesNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseTlr4 protein, mouseToll-Like Receptor 4intestinekidneyliverLPSlungvaried inflammatory reaction

Identifiers

PMID31446815
PMCPMC6720225
OpenAlexW2969413466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.