Evidence map›Paper›PMID 31446782›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2020

Differences in the Tensor Veli Palatini Muscle and Hearing Status in Children With and Without 22q11.2 Deletion Syndrome.

Jamie L Perry, Katelyn J Kotlarek, Kelly Spoloric, Adriane Baylis, Lakshmi Kollara, Jonathan M Grischkan, Richard Kirschner, David Gregory Bates, Mark Smith, Ursula Findlen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jamie L PerryDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-7866-9159
Katelyn J KotlarekDivision of Communication Disorders, University of Wyoming, Laramie, WY, USA.
Kelly SpoloricDepartment of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.
Adriane BaylisSection of Plastic and Reconstructive Surgery, Nationwide Children's Hospital, Columbus, OH, USA.
Lakshmi KollaraDepartment of Clinical Health Sciences, Texas A&M University, Kingsville, TX, USA.
Jonathan M GrischkanDepartment of Pediatric Otolaryngology, Nationwide Children's Hospital, Columbus, OH, USA.
Richard KirschnerPlastic and Reconstructive Surgery, Nationwide Children's Hospital, Columbus, OH, USA.
David Gregory BatesDepartment of Radiology, Nationwide Children's Hospital, Columbus, OH, USA.
Mark SmithRadiology at The Ohio State University College of Medicine, Columbus, OH, USA.
Ursula FindlenDivision of Clinical Therapies, Audiology Department, Nationwide Children's Hospital, Columbus, OH, USA.
Nationwide Children's Hospital · USEast Carolina University · USTexas A&M University – Kingsville · USThe Ohio State University · USUniversity of Wyoming · US

Funding

MRI Analyses of the Velopharyngeal Mechanism among Different Adult PopulationsR03DC009676 · NIDCD · ILLINOIS STATE UNIVERSITY · PI PERRY, JAMIE L · 2009 to 2011
$441k
Investigation of Anatomical and Physiological Changes Following the Use of a Pedicled Buccal Fat Pad Graft During Primary PalatoplastyF31DE027878 · NIDCR · EAST CAROLINA UNIVERSITY · PI KOTLAREK, KATELYN JOY · 2018 to 2019
$48k
NIDCD NIH HHS R03 DC009676NIDCR NIH HHS F31 DE027878
6 · The paper itself

Abstract

purposeTo investigate the dimensions of the tensor veli palatini (TVP) muscle using high image resolution 3-dimensional magnetic resonance imaging (MRI) of the soft palate among children with normal velopharyngeal and craniofacial anatomy and to compare values to individuals with a diagnosis of 22q11.2 deletion syndrome (22q11DS). We also sought to determine whether there is a relationship between hypoplasia of the TVP and severity of middle ear dysfunction and hearing loss.

methodsThree-dimensional MRI were used to collect and analyze data obtained across 53 children between 4 and 12 years of age, including 40 children with normal velopharyngeal and craniofacial anatomy and 13 children with a diagnosis of 22q11.2 DS. Tensor veli palatini muscle length, thickness, and volume as well as bihamular distance were compared among participant groups.

resultsA Welch's

conclusionThe TVP muscle is substantially reduced in volume, length, and thickness in children with 22q11DS. These findings serve as preliminary support for the association of patient hearing and otologic severity and TVP dysmorphology.

Indexed as

CraniosynostosesDiGeorge SyndromeEustachian TubeMarfan SyndromeChildHumansPalatal Muscles22q11.2 deletion syndrome3-dimensional reconstructioneustachian tube dysfunctionmagnetic resonance imagingmorphologytensor veli palatini

Identifiers

PMID31446782
PMCPMC7007822
OpenAlexW2970465030

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.