Evidence map›Paper›PMID 31446515›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Depressive symptoms, physical symptoms, and health-related quality of life among older adults with HIV.

Blair Olson, Wilson Vincent, Jaimie P Meyer, Trace Kershaw, Kathleen J Sikkema, Timothy G Heckman, Nathan B Hansen

Open access · greenAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Blair OlsonSchool of Public Health, Yale University, New Haven, CT, USA.
Wilson VincentSchool and Department of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA, USA.
Jaimie P MeyerSchool of Public Health, Yale University, New Haven, CT, USA.
Trace KershawSchool of Public Health, Yale University, New Haven, CT, USA.
Kathleen J SikkemaDepartment of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Timothy G HeckmanCollege of Public Health, University of Georgia, Athens, GA, USA.
Nathan B HansenCollege of Public Health, University of Georgia, Athens, GA, USA. nhansen@uga.edu.
Yale University · USUniversity of Georgia · USColumbia University · USUniversity of California, San Francisco · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
INTERDISCIPLINARY HIV PREVENTION TRAINING PROGRAMT32MH020031 · NIMH · YALE UNIVERSITY · PI Trace S Kershaw · 1999 to 2026
$12.1M
A Coping Intervention for HIV-Infected Older AdultsR01MH067566 · NIMH · OHIO UNIVERSITY ATHENS · PI HECKMAN, TIMOTHY GLENN · 2004 to 2006
$1.9M
Sleep and neural plasticity in developing neocortexR01MH067568 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI FRANK, MARCOS G · 2002 to 2005
$1.1M
An Intervention to Increase Retention in Care among HIV-Positive Black MenK23MH111402 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VINCENT, WILSON · 2017 to 2020
$1.0M
Intervention for HIV+ Adults With Childhood Sexual AbuseK23MH076671 · NIMH · YALE UNIVERSITY · PI HANSEN, NATHAN B · 2006 to 2010
$900k
Evaluating and Improving HIV Outcomes in Community-Based Women who Interface withK23DA033858 · NIDA · YALE UNIVERSITY · PI MEYER, JAIMIE · 2012 to 2016
$821k
Doris Duke Charitable Foundation 2017080NCATS NIH HHS UL1 TR001863NIDA NIH HHS K23 DA033858NIMH NIH HHS K23 MH076671NIMH NIH HHS K23 MH111402NIMH NIH HHS P30 MH062246NIMH NIH HHS P30 MH062294NIMH NIH HHS R01 MH067566NIMH NIH HHS R01 MH067568NIMH NIH HHS R01-MH067568NIMH NIH HHS T32 MH019105NIMH NIH HHS T32 MH020031
6 · The paper itself

Abstract

purposeIn the United States, approximately 45% of persons living with HIV (PLHIV) are ≥ 50 years of age. Many older PLHIV have multi-morbidities that complicate HIV infection and/or interfere with, or are exacerbated by, antiretroviral treatment. Physical health symptoms and psychiatric disorders, particularly depression, can worsen life quality in older PLHIV.

methodsThis study assessed associations among physical symptoms, indicators of HIV-related health status (i.e., time since diagnosis; ever diagnosed with AIDS; having attained viral suppression), depressive symptoms, and health-related quality of life (HRQoL) in older PLHIV. Regression analyses examined data from 296 PLHIV ≥ 50 years of age living in Cincinnati, OH, Columbus, OH, and New York City.

resultsDepressive symptoms and physical symptoms, particularly those related to appearance and sexual functioning, most strongly predicted HRQoL. Indicators of HIV health status did not significantly predict HRQoL. Depressive symptoms were a particularly robust predictor of HRQoL, even when accounting for physical health symptoms.

conclusionFindings suggest that symptom management is critical to HRQoL in older PLHIV, and symptoms related to physical appearance and sexual functioning should not be overlooked in this growing population.

Indexed as

AgedAgingAnti-Retroviral AgentsDepressionDepressive DisorderFemaleHealth StatusHIV InfectionsHumansMaleMiddle AgedNew York CityQuality of LifeUnited StatesAnti-Retroviral AgentsAgingDepressionHIV/AIDSPhysical symptomsQuality of life

Identifiers

PMID31446515
PMCPMC6868331
OpenAlexW2969354457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.