Evidence map›Paper›PMID 31446474›Full record

ArticlePediatric cardiology2019

Impact of Ethnicity on the Prevalence of Early Repolarization Pattern in Children: Comparison Between Caucasian and African Populations.

Antonio Creta, Michele Arigliani, Giuseppe di Gioia, Roberta Lapenna, Fabio Quintarelli, Mario Fittipaldi, Vincenzo Antinolfi, Ranieri Bettini, Davide Costanzo, Alessandro Cruciani and 11 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Antonio CretaBarts Heart Centre, St. Bartholomew's Hospital, West Smithfield, London, EC1A7BE, UK. creta.antonio@gmail.com.ORCID http://orcid.org/0000-0002-7743-0143
Michele AriglianiDivision of Pediatrics, Department of Medicine, University Hospital of Udine, Udine, Italy.
Giuseppe di GioiaUnit of Cardiology, Campus Bio-Medico University of Rome, Rome, Italy.
Roberta LapennaHospital of Sant'Antonio, San Daniele del Friuli, Italy.
Fabio QuintarelliUnit of Pediatrics, Campus Bio-Medico University of Rome, Rome, Italy.
Mario FittipaldiDepartment of Paediatric Cardiology, Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital for Children's NHS Trust, London, United Kingdom.
Vincenzo AntinolfiUnit of Anaesthesia, Intensive Care and Pain Management, Campus Bio-Medico University of Rome, Rome, Italy.
Ranieri BettiniCardiothoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Davide CostanzoCampus Bio-Medico University of Rome, Rome, Italy.
Alessandro CrucianiUnit of Neurology, Campus Bio-Medico University of Rome, Rome, Italy.
Stefano Di BerardinoCampus Bio-Medico University of Rome, Rome, Italy.
Riccardo GiorginoUnit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, Rome, Italy.
Umberto SatrianoCampus Bio-Medico University of Rome, Rome, Italy.
Giuseppe MangiameliDepartment of Thoracic Surgery and Lung Transplantation, Paris Descartes University, Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris, Paris, France.
Dario SutCardiothoracic Department, Division of Cardiology, University Hospital of Udine, Udine, Italy.
Marco CaricatoGeriatric Surgery Unit, Campus Bio-Medico University of Rome, Rome, Italy.
Paola CogoDivision of Pediatrics, Department of Medicine, University Hospital of Udine, Udine, Italy.
Alessandro ProclemerCardiothoracic Department, Division of Cardiology, University Hospital of Udine, Udine, Italy.
Giovanni MottiniCampus Bio-Medico University of Rome, Rome, Italy.
Pier D LambiaseBarts Heart Centre, St. Bartholomew's Hospital, West Smithfield, London, EC1A7BE, UK.
Rui ProvidênciaBarts Heart Centre, St. Bartholomew's Hospital, West Smithfield, London, EC1A7BE, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The patterns and prevalence of early repolarization pattern (ER) in pediatric populations from ethnic backgrounds other than Caucasian have not been determined. Black African children (ages 4-12) from north-west Madagascar were prospectively recruited and their ECGs compared with those of age- and sex-matched Caucasian ethnicity individuals. ER was defined by ≥ 0.1 mV J-point elevation in at least two contiguous inferior and/or lateral ECG leads. A total of 616 children were included. There was a trend toward a higher frequency of ER in the Africans compared to the Caucasians (23.3% vs. 17.1%, respectively, p = 0.053). The subtype (slurred vs. notched) and location of ER (lateral, inferior, or inferior-lateral) were significantly different in the two groups (p < 0.001 and p = 0.020, respectively). There was no significant difference in the number of high-risk ECG features of ERP (i.e., horizontal/descendent pattern, inferior or inferior-lateral location or J-waves ≥ 2 mm) between African and Caucasian children. On the multivariate analysis, African ethnicity was an independent predictive factor of ER (OR 3.57, 95% CI 2.04-6.25, p < 0.001). African children have an increased risk of ER compared to Caucasian counterparts. Future studies should clarify the clinical and prognostic significance of ER in the pediatric population, and whether ethnicity has an impact on the outcomes.

Indexed as

Arrhythmias, CardiacBlack PeopleChildChild, PreschoolElectrocardiographyFemaleHumansMaleWhite PeopleEarly repolarizationEthnicityPediatricsSudden death

Identifiers

PMID31446474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.