Evidence map›Paper›PMID 31446314›Full record

ArticleNeuroImage. Clinical2019

FMRI response to acute psychological stress differentiates patients with psychogenic non-epileptic seizures from healthy controls - A biochemical and neuroimaging biomarker study.

Jane B Allendorfer, Rodolphe Nenert, Kathleen A Hernando, Jennifer L DeWolfe, Sandipan Pati, Ashley E Thomas, Neil Billeaud, Roy C Martin, Jerzy P Szaflarski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Stress Classification Using Brain Signals Based on LSTM Network.Computational intelligence and neuroscience · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jane B AllendorferDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: jallendorfer@uabmc.edu.
Rodolphe NenertDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Kathleen A HernandoDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Jennifer L DeWolfeDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Sandipan PatiDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Ashley E ThomasDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Neil BilleaudDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Roy C MartinDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Jerzy P SzaflarskiDepartment of Neurology, The UAB Epilepsy Center, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USUniversity of Alabama at Birmingham Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated psychological stress response in the brain regions involved in emotion-motor-executive control in psychogenic non-epileptic seizures (PNES). 12 PNES patients and 12 healthy controls (HCs) underwent stress task and resting state functional MRI (fMRI), mood and quality of life (QOL) assessments, and measurements of salivary cortisol, alpha-amylase, and heart rate. Group differences were assessed, and we correlated beta values from a priori selected brain regions showing stress task fMRI group differences with other stress response measures. We also used the regions showing stress task fMRI group differences as seeds for resting state functional connectivity (rs-FC) analysis. Mood and QOL were worse in PNES versus HCs. Physiological and assessment measures were similar except 'Planful Problem Solving' coping that was greater for HCs (p = .043). Perceived stress associated negatively with heart rate change (r

Indexed as

AdultFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingSeizuresStress, PsychologicalAlpha-amylaseCortisolEmotionfMRIPsychogenic non-epileptic seizures (PNES)Psychological stress

Identifiers

PMID31446314
PMCPMC6718876
OpenAlexW2965276798

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.