Evidence map›Paper›PMID 31446064›Full record

Observational studyChest2020

COPD Assessment Test in Bronchiectasis: Minimum Clinically Important Difference and Psychometric Validation: A Prospective Study.

David De la Rosa Carrillo, Casilda Olveira, Marta García-Clemente, Rosa-María Girón-Moreno, Rosa Nieto-Royo, Annie Navarro-Rolon, Concepción Prados-Sánchez, Oriol Sibila, Miguel-Ángel Martínez-García

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Patient report outcome measures for Spanish-speaking adults with bronchiectasis: systematic review of measurement properties.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
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  5. The importance of symptoms in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  6. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

David De la Rosa CarrilloPneumology Service, Hospital Plató, Barcelona, Spain.
Casilda OlveiraPneumology Service, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga/Universidad de Málaga, Málaga, Spain. Electronic address: casi1547@separ.es.
Marta García-ClementePneumology Service, Hospital Universitario Central de Asturias, Oviedo, Spain.
Rosa-María Girón-MorenoPneumology Service, Hospital de la Princesa, Madrid, Spain.
Rosa Nieto-RoyoPneumology Service, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Annie Navarro-RolonPneumology Service, Hospital Mutua de Terrassa, Terrassa, Spain.
Concepción Prados-SánchezPneumology Service, Hospital Universitario La Paz-IS Carlos III, Madrid, Spain.
Oriol SibilaPneumology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Miguel-Ángel Martínez-GarcíaPneumology Service, Hospital Universitario y Politécnico de La Fe, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth-related quality of life (QoL) is one of the most important end points in bronchiectasis (BE). However, the majority of health-related QoL questionnaires are time-consuming or not validated in BE. The COPD Assessment Test (CAT) is an easy-to-use questionnaire. The objective of this study was to perform a complete validation of the CAT in BE.

methodsThis was an observational, multicenter, prospective study in patients with BE. Psychometric properties of the CAT were measured: internal consistency (Cronbach α), repeatability (test-retest; intraclass correlation coefficient), discriminant validity (correlation with severity scores), convergent validity (correlation with some validated QoL questionnaire and other clinical variables of interest), longitudinal validity (measuring before and after each exacerbation during follow-up to determine the sensitivity to change and responsiveness), predictive validity to future exacerbations, and finally minimum clinically important difference.

resultsNinety-six patients were included and followed up for 1 year. Their mean age was 62.2 (15.6) years (79.2% women). The CAT showed excellent internal consistency (α, 0.95) and repeatability (intraclass correlation coefficient, 0.95). The validity of the CAT was excellent in all the measures (almost all with a Pearson coefficient > 0.40) except for the correlations with severity scores (Pearson coefficient between 0.22 and 0.26). Sensitivity to change before and after exacerbations was set at between 5.4 and 5.8 points. A CAT value ≥ 10 points showed prognostic value for patients with more than one exacerbation, and finally the minimum clinically important difference was set at 3 points.

conclusionsThe CAT presented excellent psychometric properties and is a questionnaire that is easy to use and interpret in patients with BE.

Indexed as

PsychometricsQuality of LifeBronchiectasisFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveReproducibility of ResultsSeverity of Illness IndexSpainSurveys and QuestionnairesSymptom AssessmentbronchiectasisCOPD Assessment Testquality of life

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.