Evidence map›Paper›PMID 31445886›Full record

ArticleMolecular cell2019

Regulation of Co-transcriptional Pre-mRNA Splicing by m

Katherine I Zhou, Hailing Shi, Ruitu Lyu, Adam C Wylder, Żaneta Matuszek, Jessica N Pan, Chuan He, Marc Parisien, Tao Pan

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 263 papers.

0numbers the graph read from it
0cells of the map it votes in
263citing papers in PubMed
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

263 citing papers in PubMed, 370 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. mNature reviews. Neuroscience · 2026
    Review
  7. The Role of NMedComm · 2026
    Review
  8. Review
  9. Methylation marks breast cancer metastasis: The roles of mThe Journal of biological chemistry · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. The mFrontiers in cell and developmental biology · 2026
    Review
  16. Review
  17. The "cutting edge" of non-canonical RNA splicing.Frontiers in molecular biosciences · 2026
    Review
  18. Review
  19. Review
  20. NResearch (Washington, D.C.) · 2026
    Article

203 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Katherine I ZhouDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA; Medical Scientist Training Program, The University of Chicago, Chicago, IL 60637, USA.
Hailing ShiDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Ruitu LyuDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Adam C WylderDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA.
Żaneta MatuszekDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.
Jessica N PanDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.
Chuan HeDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA; Institute of Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Marc ParisienThe Alan Edwards Centre for Research on Pain, Department of Dentistry, McGill University, Montréal, QC H3A 0G14, Canada. Electronic address: marc.parisien@mcgill.ca.
Tao PanDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA; Institute of Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA. Electronic address: taopan@uchicago.edu.
University of Chicago · USHoward Hughes Medical Institute · USMcGill University · CA

Funding

MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Recognition and mechanism of N6-methyl adenosine modificationsR01GM113194 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 2015 to 2022
$2.5M
Role of m6A in HNRNPG protein localization and HNRNPG-regulated alternative splicingF30GM120917 · NIGMS · UNIVERSITY OF CHICAGO · PI ZHOU, KATHERINE ISMEI · 2016 to 2018
$147k
NHGRI NIH HHS RM1 HG008935NIGMS NIH HHS F30 GM120917NIGMS NIH HHS R01 GM113194NIGMS NIH HHS T32 GM007281
6 · The paper itself

Abstract

N

Indexed as

Alternative SplicingTranscription, GeneticAdenosineAmino Acid MotifsBinding SitesExonsHEK293 CellsHeterogeneous-Nuclear RibonucleoproteinsHumansProtein BindingRNA, MessengerRNA Polymerase IIRNA PrecursorsStructure-Activity RelationshipAdenosineHeterogeneous-Nuclear RibonucleoproteinsN-methyladenosineRBMX protein, humanRNA, MessengerRNA Polymerase IIRNA Precursorsco-transcriptionCTD domainhnRNPGlow complexity regionm6ARBMXRGGRNA polymerase IIsplicing

Identifiers

PMID31445886
PMCPMC6778029
OpenAlexW2969469813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.