Evidence map›Paper›PMID 31445873›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2020

Effects of Childhood and Adult Persistent Attention-Deficit/Hyperactivity Disorder on Risk of Motor Vehicle Crashes: Results From the Multimodal Treatment Study of Children With Attention-Deficit/Hyperactivity Disorder.

Arunima Roy, Annie A Garner, Jeffery N Epstein, Betsy Hoza, J Quyen Nichols, Brooke S G Molina, James M Swanson, L Eugene Arnold, Lily Hechtman

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00000388 (Multimodal Treatment Study of Children With ADHD), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00000388 phase4completednot on this map

Multimodal Treatment Study of Children With ADHD

TypeinterventionalSponsorNYU Langone HealthRan1998 to 1999ConditionsAttention Deficit Disorder With Hyperactivity, Substance-related Disorders, Dyssocial BehaviorArmsPsychosocial treatment, Anti-ADHD medication, Assessment-and-Referral
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Real-World Crash Circumstances Among Newly Licensed Adolescent Drivers With and Without Attention-Deficit/Hyperactivity Disorder.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Article
  5. Article
  6. Editorial: Paving the Way Toward Improving Safety Among Drivers With Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Arunima RoyThe Royal's Institute of Mental Health Research, University of Ottawa, Ontario, Canada.
Annie A GarnerSaint Louis University, St. Louis, Missouri.
Jeffery N EpsteinUniversity of Cincinnati College of Medicine and the Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Ohio.
Betsy HozaUniversity of Vermont, Burlington.
J Quyen NicholsUniversity of Vermont, Burlington.
Brooke S G MolinaUniversity of Pittsburgh School of Medicine, Pennsylvania.
James M SwansonChild Development Center, School of Medicine, University of California, Irvine.
L Eugene ArnoldNisonger Center, Ohio State University, Columbus.
Lily HechtmanDivision of Child Psychiatry, Montreal Children's Hospital, McGill University, Quebec, Canada. Electronic address: lhechtman@hotmail.com.
University of Vermont · USCincinnati Children's Hospital Medical Center · USMontreal Children's Hospital · CASaint Louis University · USThe Ohio State University Wexner Medical Center · USUniversity of California, Irvine · USUniversity of Ottawa · CAUniversity of Pittsburgh · US

Funding

Pathways to adult substance use and abuse from childhood ADHD in the MTAR01DA039881 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2015 to 2018
$1.1M
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12009 · NIMH · PI HINSHAW, STEPHEN · 2007 to 2007
$443k
FOLLOW UP OF THE MULTIMODAL TREATMETN STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12010 · NIMH · PI MOLINA, BROOKE S. G. · 2007 to 2007
$421k
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12012 · NIMH · PI WELLS, KAREN · 2007 to 2007
$417k
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12011 · NIMH · PI SWANSON, JAMES · 2007 to 2007
$344k
FOLLOW UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12007 · NIMH · PI GREENHILL, LAURENCE L. · 2007 to 2007
$310k
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12008 · NIMH · PI HECHTMAN, LILY · 2007 to 2007
$304k
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION DEFICIT HN01MH12004 · NIMH · PI ABIKOFF, HOWARD BARRY · 2007 to 2007
$214k
PHARMACOLOGIC AND PSYCHOSOCIAL INTERVENTIONS FOR ADHDU01MH050461 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HINSHAW, STEPHEN P · 1992 to 2000
$17k
MULTISITE MULTIMODAL TREATMENT STUDY OF ADHD/ADDU01MH050453 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ABIKOFF, HOWARD B · 1992 to 2000
$17k
MULTISITE MULTIMODALITY TREATMENT STUDY OF ADHD/ADDU01MH050440 · NIMH · UNIVERSITY OF CALIFORNIA IRVINE · PI SWANSON, JAMES M · 1992 to 2000
$17k
PHARMACOLOGICAL AND PSYCHOSOCIAL TREATMENT FOR ADHDU01MH050467 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PELHAM, WILLIAM E · 1992 to 2000
$17k
NIDA NIH HHS N01 DA085548NIDA NIH HHS N01 DA085549NIDA NIH HHS N01 DA085550NIDA NIH HHS N01 DA085551NIDA NIH HHS N01 DA085552NIDA NIH HHS N01 DA085553NIDA NIH HHS N01 DA085554NIDA NIH HHS R01 DA039881NIMH NIH HHS N01MH12004NIMH NIH HHS N01MH12007NIMH NIH HHS N01MH12008NIMH NIH HHS N01MH12009NIMH NIH HHS N01MH12010NIMH NIH HHS N01MH12011NIMH NIH HHS N01MH12012NIMH NIH HHS U01 MH050440NIMH NIH HHS U01 MH050453NIMH NIH HHS U01 MH050461NIMH NIH HHS U01 MH050467
6 · The paper itself

Abstract

objectiveTo determine motor vehicle crash (MVC) risk in adults with a history of childhood attention-deficit/hyperactivity disorder (ADHD) and persistent ADHD symptoms.

methodParticipants with (n = 441) and without (n = 239; local normative comparison group) childhood ADHD from the Multimodal Treatment of Attention-Deficit/Hyperactivity Disorder (MTA) Study were included. Participants provided self-reports on total number of MVCs they had been involved in and the time of licensure. Driving experience was estimated as the number of months since licensure. Total number of MVCs by adulthood was regressed on baseline ADHD status adjusting for sex, age at follow-up, driving experience, baseline oppositional defiant disorder/conduct disorder comorbidity, baseline household income level, adult oppositional defiant disorder/conduct disorder symptoms, adolescent and adult substance use, and adult antisocial personality disorder symptoms. We repeated the analysis using adult ADHD status (persistent versus desistant versus local normative comparison group) and symptom level as the predictor variables. Results are presented as incidence rate ratio (IRR) and CI.

resultsChildhood ADHD was associated with a higher number of MVCs (IRR = 1.45, CI = 1.15-1.82), and adult ADHD symptom persistence was associated with more MVCs than desistance (IRR = 1.46, CI = 1.14-1.86). ADHD desistance was not associated with a significantly increased risk for MVCs compared with the local normative comparison group (IRR = 1.24, CI = 0.96-1.61). Concurrent symptoms of inattention and hyperactivity/impulsivity predicted MVC risk.

conclusionPersistence of ADHD into adulthood is a stronger predictor of MVC risk than childhood-limited ADHD. CLINICAL TRIAL REGISTRATION INFORMATION: Multimodal Treatment of Attention Deficit Hyperactivity Disorder (MTA) Study; https://clinicaltrials.gov; NCT00000388.

Indexed as

Attention Deficit Disorder with HyperactivityAccidents, TrafficAdolescentAdultAttention Deficit and Disruptive Behavior DisordersChildCombined Modality TherapyComorbidityHumansMotor VehiclesADHD persistenceattention-deficit/hyperactivity disorder (ADHD)comorbiditydrivingmotor vehicle crashes

Identifiers

PMID31445873
PMCPMC9747063
OpenAlexW2969584000

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.