ArticleJournal of vascular surgery2020
A low-cost, wireless near-infrared spectroscopy device detects the presence of lower extremity atherosclerosis as measured by computed tomographic angiography and characterizes walking impairment in peripheral artery disease.
Article in Journal of vascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- ACR Appropriateness Criteria® Lower Extremity Arterial Claudication-Imaging Assessment for Revascularization: 2022 Update.Journal of the American College of Radiology : JACR · 2022Guideline
- Moderate dose of dietary nitrate improves skeletal muscle microvascular function in patients with peripheral artery disease.Microvascular research · 2023Trial
- Muscle oxygenation regulation in physical therapy and rehabilitation.Medical gas research · 2026Review
- Exercise oximetry in clinical practice: A single-centre perspective on procedure and techniques.Experimental physiology · 2025Review
- Insights From Bone and Muscle Oxygenation Toward a More Comprehensive Model of Tissue Healing.The Journal of surgical research · 2025Article
- Incremental shuttle walking test for calf muscle oxygenation assessment in peripheral arterial disease: a cross-sectional study.Scientific reports · 2025Article
- Multi-modality imaging for assessment of the microcirculation in peripheral artery disease: Bench to clinical practice.American heart journal plus : cardiology research and practice · 2024Article
- Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease.American journal of physiology. Heart and circulatory physiology · 2024Review
- Joint Angle Variability Is Altered in Patients with Peripheral Artery Disease after Six Months of Exercise Intervention.Entropy (Basel, Switzerland) · 2022Article
- Aging alters gastrocnemius muscle hemoglobin oxygen saturation (StOEuropean journal of applied physiology · 2022Article
- Impaired microcirculatory function, mitochondrial respiration, and oxygen utilization in skeletal muscle of claudicating patients with peripheral artery disease.American journal of physiology. Heart and circulatory physiology · 2022Article
- Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia.Biochimica et biophysica acta. Molecular basis of disease · 2022Article
- High optode-density wearable diffuse optical probe for monitoring paced breathing hemodynamics in breast tissue.Journal of biomedical optics · 2021Article
- Gait variability is affected more by peripheral artery disease than by vascular occlusion.PloS one · 2021Article
- Skeletal Muscle Mitochondrial Dysfunction and Oxidative Stress in Peripheral Arterial Disease: A Unifying Mechanism and Therapeutic Target.Antioxidants (Basel, Switzerland) · 2020Review
- Collateral Development and Arteriogenesis in Hindlimbs of Swine After Ligation of Arterial Inflow.The Journal of surgical research · 2020Article
- Ankle-brachial index: more than a diagnostic test?Archivos peruanos de cardiologia y cirugia cardiovascularReview
Corrections and comments
- Commented on by
- Commented on byReply.2020
- Commented on by
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatients with peripheral artery disease (PAD) who experience intermittent claudication report a range of symptoms. Patients with symptoms other than classically described intermittent claudication may be at the highest risk for functional decline and mobility loss. Therefore, technologies allowing for characterization of PAD severity are desirable. Near-infrared spectroscopy (NIRS) allows for measurements of muscle heme oxygen saturation (StO
methodsWe recruited 40 patients with PAD and 10 control participants. All patients with PAD completed a computed tomographic angiography, 6-minute walk test, and a standardized treadmill test. Controls completed a 540-second treadmill test for comparison. StO
resultsPatients with PAD experienced claudication onset at a median of 108 seconds with a median peak walking time of 288 seconds. The baseline StO
conclusionsIn this initial evaluation of a novel, low-cost NIRS device, lower extremities affected by PAD exhibited characteristic changes in calf muscle StO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.