Evidence map›Paper›PMID 31445780›Full record

ReviewTrends in cognitive sciences2019

Awake Reactivation of Prior Experiences Consolidates Memories and Biases Cognition.

Arielle Tambini, Lila Davachi

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. Post-encoding administration of oxytocin selectively enhances memory consolidation of male faces in females.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Trial
  2. Article
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  4. The hippocampus as a generative model.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  5. Article
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  11. A prelimbic molecular clock of protein synthesis for memory persistence.bioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Resting after learning or repeating the learned?Psychonomic bulletin & review · 2025
    Article
  14. Article
  15. Updating social evaluation during sleep.NPJ science of learning · 2025
    Article
  16. Replay in the human visual cortex during brief task pauses is linked to implicit learning of successor representations.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Review
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  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arielle TambiniHelen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.
Lila DavachiDepartment of Psychology, Columbia University, New York, NY, USA; Nathan Kline Institute, Orangeburg, NY, USA. Electronic address: ld24@columbia.edu.

Funding

Medial temporal lobe contributions to episodic memoryR01MH074692 · NIMH · NEW YORK UNIVERSITY · PI DAVACHI, LILA · 2007 to 2021
$5.9M
Behavioral relevance of hippocampal pattern separation and completion processesF31MH092055 · NIMH · NEW YORK UNIVERSITY · PI TAMBINI, ARIELLE B · 2010 to 2012
$94k
NIMH NIH HHS F31 MH092055NIMH NIH HHS R01 MH074692
6 · The paper itself

Abstract

After experiences are encoded into memory, post-encoding reactivation mechanisms have been proposed to mediate long-term memory stabilization and transformation. Spontaneous reactivation of hippocampal representations, together with hippocampal-cortical interactions, are leading candidate mechanisms for promoting systems-level memory strengthening and reorganization. While the replay of spatial representations has been extensively studied in rodents, here we review recent fMRI work that provides evidence for spontaneous reactivation of nonspatial, episodic event representations in the human hippocampus and cortex, as well as for experience-dependent alterations in systems-level hippocampal connectivity. We focus on reactivation during awake post-encoding periods, relationships between reactivation and subsequent behavior, how reactivation is modulated by factors that influence consolidation, and the implications of persistent reactivation for biasing ongoing perception and cognition.

Indexed as

CognitionMemory ConsolidationMemory, EpisodicBiasBrainCerebral CortexFunctional NeuroimagingHippocampusHumansMemoryWakefulnessawake resthippocampal interactionshippocampusmemory consolidationreactivationreplay

Identifiers

PMID31445780
PMCPMC6907733

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.