Evidence map›Paper›PMID 31445751›Full record

Trial reportOphthalmology2020

Effects of Omega-3 Supplementation on Exploratory Outcomes in the Dry Eye Assessment and Management Study.

Marko Oydanich, Maureen G Maguire, Maxwell Pistilli, Pedram Hamrah, Jack V Greiner, Meng C Lin, Penny A Asbell, Dry Eye Assessment and Management Study Research Group

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02128763 (Dry Eye Assessment and Management Study), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02128763 phase3completednot on this map

Dry Eye Assessment and Management Study

TypeinterventionalSponsorUniversity of PennsylvaniaRan2014 to 2020Enrolled535ConditionsDry EyeArmsOmega-3 supplements, Placebo
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Diagnostic methods for managing dry eyes.World journal of methodology · 2025
    Article
  4. Article
  5. Observational
  6. Article
  7. Sex Differences in the Lacrimal Gland: Implications for Dry Eye Disease.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marko OydanichDepartment of Cell Biology and Molecular Medicine, Rutgers-New Jersey Medical School, Newark, New Jersey.
Maureen G MaguireDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: maguirem@pennmedicine.upenn.edu.
Maxwell PistilliDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania.
Pedram HamrahCornea Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts.
Jack V GreinerSchepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
Meng C LinClinical Research Center, Berkeley Optometry, University of California, Berkeley, Berkeley, California.
Penny A AsbellHamilton Eye Institute, University of Tennessee Health Science Center (UTHSC), Memphis Tennessee.
Dry Eye Assessment and Management Study Research Group

Funding

The Dry Eye Evaluation And Management (DREAM) Study: Coordinating CenterU10EY022879 · NEI · UNIVERSITY OF PENNSYLVANIA · PI MAGUIRE, MAUREEN G · 2013 to 2018
$7.3M
Dry Eye Evaluation and Management (DREAM) StudyU10EY022881 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ASBELL, PENNY · 2013 to 2020
$2.2M
NEI NIH HHS U10 EY022879NEI NIH HHS U10 EY022881
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Docosahexaenoic AcidsDouble-Blind MethodDry Eye SyndromesEicosapentaenoic AcidFatty Acids, Omega-3FluorophotometryHumansLipid MetabolismMatrix Metalloproteinase 9Osmolar ConcentrationTearsTreatment OutcomeDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3Matrix Metalloproteinase 9MMP9 protein, human

Identifiers

PMID31445751
PMCPMC6926153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.