Evidence map›Paper›PMID 31445682›Full record

ArticleBiophysical journal2019

Conformational Flexibility of p150

Changmiao Guo, John C Williams, Tatyana Polenova

Abstract read
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Changmiao GuoDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware.
John C WilliamsDepartment of Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California.
Tatyana PolenovaDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware. Electronic address: tpolenov@udel.edu.

Funding

Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

Microtubule (MT)-associated proteins perform diverse functions in cells. These functions are dependent on their interactions with MTs. Dynactin, a cofactor of dynein motor, assists the binding of dynein to various organelles and is crucial to the long-distance processivity of dynein-based complexes. The largest subunit of dynactin, the p150

Indexed as

Amino Acid SequenceAnimalsCattleDynactin ComplexMagnetic Resonance SpectroscopyMicrotubulesPolymerizationProtein BindingProtein ConformationProtein SubunitsSolutionsTemperatureTubulinDynactin ComplexProtein SubunitsSolutionsTubulin

Identifiers

PMID31445682
PMCPMC6731383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.