Evidence map›Paper›PMID 31444649›Full record

ArticleMikrochimica acta2019

A nanocomposite prepared from reduced graphene oxide, gold nanoparticles and poly(2-amino-5-mercapto-1,3,4-thiadiazole) for use in an electrochemical sensor for doxorubicin.

Mohammad Hossein Ghanbari, Faezeh Shahdost-Fard, Hamid Salehzadeh, Mohammad Reza Ganjali, Maryam Iman, Mehdi Rahimi-Nasrabadi, Farhad Ahmadi

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Heterojunction of N/B/RGO and g-CEnvironmental science and pollution research international · 2021
    Article
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mohammad Hossein GhanbariChemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, 1951683759, Iran.
Faezeh Shahdost-FardDepartment of Chemistry, University of Ilam, Ilam, 69315-516, Iran.
Hamid SalehzadehFaculty of Chemistry, Kharazmi University, Tehran, 15719-14911, Iran.
Mohammad Reza GanjaliCenter of Excellence in Electrochemistry, University of Tehran, Tehran, 19839-69411, Iran.
Maryam ImanChemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, 1951683759, Iran.
Mehdi Rahimi-NasrabadiChemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, 1951683759, Iran. rahiminasrabadi@gmail.com.ORCID 0000-0003-4926-2696
Farhad AhmadiPhysiology Research Center, Iran University of Medical Sciences, Tehran, 14496-14535, Iran. farhadahmadi55@gmail.com.
Baqiyatallah University of Medical Sciences · IRIran University of Medical Sciences · IRKharazmi University · IRMedical University of Ilam · IRUniversity of Tehran · IR

Funding

Iran University of Medical Science 00
6 · The paper itself

Abstract

A nanocomposite was prepared with reduced graphene oxide, gold nanoparticles and an electropolymerized film made from 2-amino-5-mercapto-1,3,4-thiadiazole. An electrochemical sensor for doxorubicin (DOX) was constructed by modifying a glassy carbon electrode (GCE) with the nanocomposite. The modified GCE was studied by electrochemical techniques which showed it to enable highly sensitive sensing of DOX. Response (typically measured at a typical working potential of -0.56 V vs. Ag/AgCl) is linear in the 30 pM to 30 nM and 30 nM to 30 μM DOX concentration ranges, with a limit of detection (LOD) of 9 pM (at an S/N ratio of 3). The method was applied to the determination of DOX in serum and gave recoveries that ranged between 92 and 108%. Graphical abstract A combination of materials consisting of reduced graphene oxide (rGO), gold nanoparticles (AuNPs) and an electropolymerized film of 2-amino-5-mercapto-1,3,4-thiadiazole (poly-AMT, PAMT) is described. The nanocomposite was placed on a glassy carbon elkectrode (GCE) in order to fabricate an electrochemical sensor for doxorubicin (DOX).

Indexed as

Biosensing TechniquesElectrochemical TechniquesAntibiotics, AntineoplasticDoxorubicinGoldGraphiteMetal NanoparticlesMolecular ConformationNanocompositesOxidation-ReductionParticle SizePolymersSurface PropertiesThiadiazoles2-amino-5-mercapto-1,3,4-thiadiazoleAntibiotics, AntineoplasticDoxorubicinGoldgraphene oxideGraphitePolymersThiadiazolesDoxorubicinElectrochemical sensorGold nanoparticlesPoly 2-amino-5-mercapto-1,3,4-thiadiazoleReduced graphene oxide

Identifiers

PMID31444649
OpenAlexW2969362411

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.