Evidence map›Paper›PMID 31444629›Full record

ArticleJournal of autism and developmental disorders2019

Effects of Overweight or Obesity on Brain Resting State Functional Connectivity of Children with Autism Spectrum Disorder.

Chanaka N Kahathuduwa, Blake West, Ann Mastergeorge

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chanaka N KahathuduwaDepartment of Human Development and Family Studies, College of Human Sciences, Texas Tech University, 1301 Akron Street, Box 1230, Lubbock, TX, 79409-1230, USA. chanaka.kahathuduwa@ttu.edu.
Blake WestDepartment of Human Development and Family Studies, College of Human Sciences, Texas Tech University, 1301 Akron Street, Box 1230, Lubbock, TX, 79409-1230, USA.
Ann MastergeorgeDepartment of Human Development and Family Studies, College of Human Sciences, Texas Tech University, 1301 Akron Street, Box 1230, Lubbock, TX, 79409-1230, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on neurophysiological correlates of coexisting autism spectrum disorders (ASD) and overweight/obesity may elucidate mechanisms leading to the observed greater risk of obesity in children with ASD. An exploratory secondary data analysis was performed on resting state functional magnetic resonance imaging (rs-fMRI) data of children downloaded from the ABIDE Preprocessed database (n = 81). Children with isolated ASD showed hypo-connectivity between anterior and posterior default mode network (DMN) (p = 0.003; FWER). Children with coexisting ASD and overweight/obesity showed hyper-connectivity between anterior and posterior DMN (p = 0.015; FWER). More evidence is needed to confirm these contrasting rs-fMRI connectivity profiles and to explicate causal inferences regarding neurophysiological mechanisms associated with coexisting ASD and overweight/obesity.

Indexed as

AdolescentAutism Spectrum DisorderBrainBrain MappingChildFemaleHumansMagnetic Resonance ImagingMaleNerve NetNeural PathwaysOverweightPediatric ObesityAutism spectrum disorderBrainConnectomeFunctional neuroimagingMagnetic resonance imagingObesityOverweight

Identifiers

PMID31444629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.