Evidence map›Paper›PMID 31444225›Full record

ArticleeNeuro

Transcranial Direct Current Stimulation (tDCS) Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice.

Tsuneko Mishima, Terumi Nagai, Kazuko Yahagi, Sonam Akther, Yuki Oe, Hiromu Monai, Shinichi Kohsaka, Hajime Hirase

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  10. Research progress of tDCS in the treatment of ADHD.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
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  13. Article
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  19. Transcranial cortex-wide CaFrontiers in neuroscience · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Tsuneko MishimaLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan Tsuneko.mishima@riken.jp hirase@sund.ku.dk.
Terumi NagaiLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Kazuko YahagiLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Sonam AktherLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Yuki OeLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan.ORCID 0000-0001-9574-0404
Hiromu MonaiLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Shinichi KohsakaNational Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira 187-0031, Japan.
Hajime HiraseLaboratory for Neuron-Glia Circuitry, RIKEN Center for Brain Science, Wako 351-0198, Japan Tsuneko.mishima@riken.jp hirase@sund.ku.dk.ORCID 0000-0003-3806-6905
RIKEN Center for Brain Science · JPUniversity of Copenhagen · DKNational Center of Neurology and Psychiatry · JPOchanomizu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) has been reported for its beneficial effects on memory formation and various brain disorders. While the electrophysiological readout of tDCS effects is subtle, astrocytes have been demonstrated to elicit Ca

Indexed as

Adrenergic AntagonistsAnimalsAstrocytesCell MovementMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMicrogliaReceptors, AdrenergicTranscranial Direct Current StimulationAdrenergic AntagonistsReceptors, Adrenergiciba1in vivomicroglianorepinephrinetDCStwo-photon imaging

Identifiers

PMID31444225
PMCPMC6751370
OpenAlexW2969907305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.