Evidence map›Paper›PMID 31444215›Full record

ArticleDevelopment (Cambridge, England)2019

Helen M Phillips, Catherine A Stothard, Wasay M Shaikh Qureshi, Anastasia I Kousa, J Alberto Briones-Leon, Ramada R Khasawneh, Chloe O'Loughlin, Rachel Sanders, Silvia Mazzotta, Rebecca Dodds and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Epigenetic, Genetic, and Functional Germline Alterations ofCurrent issues in molecular biology · 2026
    Review
  2. Review
  3. Zoological research · 2025
    Article
  4. Towards advanced regenerative therapeutics to tackle cardio-cerebrovascular diseases.American heart journal plus : cardiology research and practice · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. PAX Genes in Cardiovascular Development.International journal of molecular sciences · 2022
    Review
  15. PAX9 in Cancer Development.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Article
  18. Morphogenesis of the Mammalian Aortic Arch Arteries.Frontiers in cell and developmental biology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 4 countries.

Helen M PhillipsInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.ORCID 0000-0003-4513-9148
Catherine A StothardInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Wasay M Shaikh QureshiInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Anastasia I KousaMemorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
J Alberto Briones-LeonInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Ramada R KhasawnehInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Chloe O'LoughlinInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Rachel SandersInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Silvia MazzottaInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Rebecca DoddsInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Kerstin SeidelInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Timothy BatesSchool of Dental Sciences, Newcastle University, Newcastle-upon-Tyne NE2 4BW, UK.
Mitsushiro NakatomiInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.
Simon J CockellBioinformatics Support Unit, Newcastle University, Newcastle-upon-Tyne NE2 4HH, UK.ORCID 0000-0002-6831-9806
Jürgen E SchneiderBiomedical Imaging, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0003-0999-5684
Timothy J MohunThe Francis Crick Institute, London NW1 1AT, UK.
René MaehrDiabetes Center of Excellence, University of Massachusetts Medical School, Worcester, MA 01605, USA.ORCID 0000-0002-9520-3382
Ralf KistInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.ORCID 0000-0003-3729-5693
Heiko PetersInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK.ORCID 0000-0002-9264-6532
Simon D BamforthInstitute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne NE1 3BZ, UK simon.bamforth@newcastle.ac.uk.ORCID 0000-0002-5666-4485
Newcastle University · GBKyushu Dental University · JPMemorial Sloan Kettering Cancer Center · USQueen Elizabeth Hospital Birmingham · GBTC Biopharm (United Kingdom) · GBThe Francis Crick Institute · GBThe Queen's Medical Research Institute · GBUniversity of Leeds · GBUniversity of Manchester · GBUniversity of Massachusetts Chan Medical School · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
British Heart Foundation FS/08/016/24741British Heart Foundation FS/16/8/31984British Heart Foundation PG/16/39/32115NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Developmental defects affecting the heart and aortic arch arteries are a significant phenotype observed in individuals with 22q11 deletion syndrome and are caused by a microdeletion on chromosome 22q11.

Indexed as

MorphogenesisAnimalsArteriesBranchial RegionCardiovascular SystemCell DifferentiationEmbryo, MammalianEndodermGene DeletionGene Regulatory NetworksHeterozygoteMice, Inbred C57BLModels, BiologicalMutationNeural CrestPAX9 Transcription FactorPAX9 Transcription FactorT-Box Domain ProteinsTbx1 protein, mouse22q11 deletion syndromeArch artery developmentNeural crestPax9Pharyngeal endodermTbx1

Identifiers

PMID31444215
PMCPMC6765178
OpenAlexW2969532097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.