Evidence map›Paper›PMID 31444206›Full record

ArticleApplied and environmental microbiology2019

Heterologous Production and Functional Characterization of Ageritin, a Novel Type of Ribotoxin Highly Expressed during Fruiting of the Edible Mushroom Agrocybe aegerita.

Annageldi Tayyrov, Sophie Azevedo, Robert Herzog, Eva Vogt, Simon Arzt, Peter Lüthy, Pie Müller, Martin Rühl, Florian Hennicke, Markus Künzler

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Annageldi TayyrovInstitute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Sophie AzevedoInstitute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Robert HerzogJunior Research Group Genetics and Genomics of Fungi, Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Frankfurt am Main, Germany.
Eva VogtInstitute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Simon ArztInstitute of Food Chemistry and Food Biotechnology, Justus Liebig University Gießen, Gießen, Germany.
Peter LüthyInstitute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Pie MüllerDepartment of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Martin RühlInstitute of Food Chemistry and Food Biotechnology, Justus Liebig University Gießen, Gießen, Germany.
Florian HennickeJunior Research Group Genetics and Genomics of Fungi, Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Frankfurt am Main, Germany florian.hennicke@senckenberg.de mkuenzle@ethz.ch.
Markus KünzlerInstitute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland florian.hennicke@senckenberg.de mkuenzle@ethz.ch.ORCID 0000-0003-1275-0629
ETH Zurich · CHJustus-Liebig-Universität Gießen · DEGoethe University Frankfurt · DESenckenberg Biodiversity and Climate Research Centre · DESwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi produce various defense proteins against antagonists, including ribotoxins. These toxins cleave a single phosphodiester bond within the universally conserved sarcin-ricin loop of ribosomes and inhibit protein biosynthesis. Here, we report on the structure and function of ageritin, a previously reported ribotoxin from the edible mushroom

Indexed as

AgaricalesAgrocybeAmino Acid SequenceAnimalsCulicidaeFungal ProteinsGene Expression Regulation, FungalLarvaMutagenesisMutationMycotoxinsRecombinant ProteinsRibonucleasesRibosomesSf9 CellsageritinFungal ProteinsMycotoxinsRecombinant ProteinsRibonucleasesbasidiomycetesentomotoxicityGAGA tetraloopgene expressionriboendonucleaseribosomerRNASRLα-sarcin

Identifiers

PMID31444206
PMCPMC6803303
OpenAlexW2971257848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.