ArticleBMJ open2019
Outcomes associated with peripherally inserted central catheters in hospitalised children: a retrospective 7-year single-centre experience.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 48 citations in OpenAlex.
- Retrospective Study of the Application Value Analysis of Ultrasound-Guided Technology in Peripheral Deep Venous Catheterization of Neonates.Disease markers · 2022Trial
- Accidental arterial PICC placement in neonatal patients: a case series.European journal of pediatrics · 2026Article
- Retrospective observational assessment of the safety, performance, and utility of an antimicrobial/antithrombogenic peripherally inserted central catheter in pediatric patients.The Journal of international medical research · 2026Observational
- Temporal and anatomic determinants of central-line-associated bloodstream infection risk in a tertiary PICU: a 3-year time-to-event and competing-risk analysis.Frontiers in pediatrics · 2026Article
- Umbilical venous catheter and peripherally inserted central catheter malposition and tip migration in neonates: A mixed methods cost analysis.International journal of nursing studies advances · 2025Article
- Peripherally Inserted Central Catheters in Newborns: A Seven-Year Single-Center Experience from a Neonatal Intensive Care Unit.Children (Basel, Switzerland) · 2025Article
- Perils of the PICC: Peripherally Inserted Central Catheter-Associated Complications and Recommendations for Prevention in Clinical Practice-A Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- Characterization of Gram-negative Bloodstream Infections in Hospitalized Australian Children and Their Clinical Outcomes.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Cannulation via the external jugular vein--An alternative to conventional peripherally inserted central catheterisation for paediatric patients.BMC pediatrics · 2023Observational
- Indications, Measurements, and Complications of Ten Essential Neonatal Procedures.International journal of pediatrics · 2023Review
- Risk factors for central venous catheter-related thrombosis in hospitalized children: a single-center a retrospective cohort study.Translational pediatrics · 2022Article
- Clinical Characteristics of Venous Thrombosis Associated with Peripherally Inserted Central Venous Catheter in Premature Infants.Children (Basel, Switzerland) · 2022Article
- Effect of implementing an Epicutaneo-Caval Catheter team in Neonatal Intensive Care Unit.The journal of vascular access · 2021Article
- Nurse Anesthetist-Performed PICC Insertion: A Prospective Longitudinal Study in a Norwegian Hospital.SAGE open nursingArticle
- A review of peripherally inserted central catheters and various types of vascular access in very small children and pediatric patients and their potential complications.Journal of medicine and lifeReview
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe use of peripherally inserted central catheters (PICCs) are an integral part of caring for hospitalised children. We sought to estimate the incidence of and identify the risk factors for complications associated with PICCs in an advanced registered nurse practitioners (ARNP)-driven programme.
designRetrospective cohort study.
settingSingle-centre, large quaternary children's hospital.
participantsHospitalised children who had PICC inserted from 1 January 2010 to 31 December 2016.
interventionsNone. MEASUREMENT AND MAIN
resultsA total of 2558 PICCs were placed during the study period. Mean age at PICC insertion was 8.7 years, mean dwell time was 17.7 days. The majority of PICCs (97.8%) were placed by ARNP. Most were placed in a single attempt (79.6%). Mean PICC residual external length outside was 2.1±2.7 cm. The rate of central line-associated bloodstream infection (CLABSI), thrombosis and significant bleeding were 1.9%, 1% and 0.2%, respectively. The CLABSI rate in infants and early childhood was higher than those aged ≥5 years (2.8%, 3.1%, respectively vs 1.3%). In a multivariate analysis after adjustment of confounding effects of race and gender, infants (OR= 2.24, CI=1.14 to 4.39, p=0.02) and early childhood cohort (OR=2.37, CI=1.12 to 5.01, p=0.02) were associated with significantly higher odds of developing CLABSI compared with ≥5 years old. In the early childhood cohort, PICCs with longer residual external catheter length (OR=1.30, 95% CI=1.07 to 1.57, p=0.008) and those placed in the operating room (OR=5.49, 95% CI=1.03 to 29.19, p=0.04), were associated with significantly greater risk of developing CLABSI.
conclusionsThe majority of PICCs were successfully placed by ARNPs on the first attempt and had a low incidence of complications. Infants required more attempts for successful PICC placement than older children. The presence of residual external catheter length and placement in the operating room were independent predictors of CLABSI in younger children.
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