Evidence map›Paper›PMID 31443618›Full record

ArticleConnective tissue research2020

Blocking substance P signaling reduces musculotendinous and dermal fibrosis and sensorimotor declines in a rat model of overuse injury.

M F Barbe, B A Hilliard, P W Fisher, A R White, S P Delany, V J Iannarone, M Y Harris, M Amin, G E Cruz, S N Popoff

Open access · bronzeAbstract read
In one paragraph

Article in Connective tissue research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Animal model for tendinopathy.Journal of orthopaedic translation · 2023
    Review
  6. Article
  7. Substance P, A Promising Therapeutic Target in Musculoskeletal Disorders.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Sustained Exposure of Substance P Causes Tendinopathy.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

M F BarbeDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.ORCID 0000-0002-5235-9803
B A HilliardDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
P W FisherDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
A R WhiteDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
S P DelanyDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
V J IannaroneDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
M Y HarrisDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
M AminDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
G E CruzDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
S N PopoffDepartment of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
Temple University · US

Funding

Biomarkers of Tissue Tolerance and Behavior in a Rat ModelR01AR056019 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI BARBE, MARY F · 2009 to 2025
$7.3M
NIAMS NIH HHS R01 AR056019
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionAnimalsCaloric RestrictionCollagen Type IConnective Tissue Growth FactorCumulative Trauma DisordersDermisDisease Models, AnimalExtracellular Signal-Regulated MAP KinasesFibrosisMuscle ProteinsMuscle, SkeletalPhosphorylationRats, Sprague-DawleyReceptors, Neurokinin-1Substance PCollagen Type IConnective Tissue Growth FactorExtracellular Signal-Regulated MAP KinasesMuscle ProteinsReceptors, Neurokinin-1Substance PTransforming Growth Factor beta1isometric pullrepetitive motion disordersrepetitive strain injuries (RSI)tendinopathyWork-related musculoskeletal disorders (WMSDs)

Identifiers

PMID31443618
PMCPMC7036028
OpenAlexW2969604967

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.