Trial reportInternational journal of environmental research and public health2019
Using a Revised Protein-Sparing Modified Fast (rPSMF) for Children and Adolescents with Severe Obesity: A Pilot Study.
Trial report in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Effect of a carbohydrate-restricted diet on weight loss in overweight and obese pediatric population: a meta-analysis of randomized controlled trials.Diabetology & metabolic syndrome · 2024Article
- Intermittent Fasting in Youth: A Scoping Review.Research square · 2024Article
- Intermittent fasting as a treatment for obesity in young people: a scoping review.npj metabolic health and disease · 2024Article
- Diagnostic challenge: A pediatric patient with severe obesity and complications of imminent death.Obesity pillars · 2023Article
- Obesity in children and adolescents: Overview of the diagnosis and management.Chronic diseases and translational medicine · 2023Review
- Benefits of Whey Proteins on Type 2 Diabetes Mellitus Parameters and Prevention of Cardiovascular Diseases.Nutrients · 2023Review
- Protein, amino acids and obesity treatment.Reviews in endocrine & metabolic disorders · 2020Review
- Strategies in the Management of Adolescent Obesity.Current pediatrics reports · 2020Article
- What to Do about Childhood Obesity?International journal of environmental research and public health · 2019Article
- Adolescents' and Parents' Perspectives of a Revised Protein-Sparing Modified Fast (rPSMF) for Severe Obesity.International journal of environmental research and public health · 2019Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Treatment options are limited for children and adolescents with severe obesity. One alternative treatment is the protein-sparing modified fast (PSMF), a low-carbohydrate, high-protein diet that can result in substantial weight loss. The aim of the study is to evaluate the adherence and efficacy of a revised PSMF (rPSMF) for severe obesity in a pediatric tertiary care weight-management program. The rPSMF with 1200-1800 calories, 40-60 g of carbohydrate/day and 1.2-1.5 g protein/kg of ideal bodyweight was implemented over 12 months. Twenty-one participants enrolled in the study. Mean age 16.2 ± 1.4 years, females (76.2%) and mean weight at baseline was 119 ± 19.9 kg. Regardless of adherence to the rPSMF, the mean weight change at 1 month was -3.7 ± 3.5 kg, (range -13.5 kg to 0.9 kg); at 3 months was -5.5 ± 5.1 kg, (range -19.3 kg to 1.8 kg) and at 6 months was -4.7 ± 6.6 kg, (range -18.3 kg to 8.6 kg). At 12 months, the mean weight change was -1.3 ± 10.6 kg (range -17.7 kg to 14.8 kg). Parent and child-reported physical and psychosocial quality of life (HRQOL) improved. Despite limited adherence, the rPSMF diet resulted in clinically significant weight loss and improved HRQOL for children and adolescents with severe obesity.
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