Evidence map›Paper›PMID 31443581›Full record

ArticleMolecules (Basel, Switzerland)2019

The Protective Role of Feruloylserotonin in LPS-Induced HaCaT Cells.

Yuzhu He, Byung-Gook Kim, Hye-Eun Kim, Qiaochu Sun, Shuhan Shi, Guowu Ma, Young Kim, Ok-Su Kim, Ok-Joon Kim

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Marine drugs · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Molecules (Basel, Switzerland) · 2023
    Article
  8. Protective effects of extracts fromFrontiers in pharmacology · 2023
    Article
  9. Article
  10. Resveratrol promotes skin wound healing by regulating the miR-212/CASP8 axis.Laboratory investigation; a journal of technical methods and pathology · 2021
    Article
  11. Anti-Inflammatory Effect of Liverwort (Plants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Yuzhu HeDepartment of Oral Pathology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0003-1137-2259
Byung-Gook KimDepartment of Oral Medicine, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Hye-Eun KimDepartment of Oral Pathology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0003-0401-7179
Qiaochu SunDepartment of Oral Pathology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0002-0713-9000
Shuhan ShiDepartment of Oral Pathology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Guowu MaDepartment of Oral and Maxillofacial Surgery, School of Stomatology, Dalian Medical University, Dalian 116044, China.
Young KimDepartment of Oral Pathology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Ok-Su KimDepartment of Periodontology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea.
Ok-Joon KimDepartment of Oral Pathology, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. js3894@jnu.ac.kr.ORCID 0000-0002-6347-1411
Chonnam National University · KRDalian Medical University · CN

Funding

the National Research Foundation of Korea (NRF) No. 2019R1F1A1044073the National Research Foundation of Korea (NRF) No.2019R1F1A1056887the National Research Foundation of Korea (NRF) No.2019R1F1A1059492
6 · The paper itself

Abstract

Epidermal inflammation is caused by various bacterial infectious diseases that impair the skin health. Feruloylserotonin (FS) belongs to the hydroxycinnamic acid amides of serotonin, which mainly exists in safflower seeds and has been proven to have anti-inflammatory and antioxidant activities. Human epidermis mainly comprises keratinocytes whose inflammation causes skin problems. This study investigated the protective effects of FS on the keratinocyte with lipopolysaccharides (LPS)-induced human HaCaT cells and elucidated its underlying mechanisms of action. The mechanism was investigated by analyzing cell viability, PGE

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAntioxidantsCell Line, TumorCell SurvivalHumansLipopolysaccharidesNF-E2-Related Factor 2NF-kappa BOxidation-ReductionProtective AgentsProtein TransportSerotoninSignal TransductionToll-Like Receptor 4Anti-Inflammatory Agents, Non-SteroidalAntioxidantsLipopolysaccharidesNFE2L2 protein, humanNF-E2-Related Factor 2NF-kappa BProtective AgentsSerotoninToll-Like Receptor 4anti-inflammationanti-oxidationepidermal inflammationferuloylserotoninHaCaT cell

Identifiers

PMID31443581
PMCPMC6749254
OpenAlexW2969992908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.