Evidence map›Paper›PMID 31443531›Full record

ArticleCancers2019

Predictive Factors of Recurrence in Patients with Differentiated Thyroid Carcinoma: A Retrospective Analysis on 579 Patients.

Fabio Medas, Gian Luigi Canu, Francesco Boi, Maria Letizia Lai, Enrico Erdas, Pietro Giorgio Calò

Abstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Impact of post-total thyroidectomy thyroglobulin levels on recurrence in patients with differentiated  thyroid cancer at a tertiary care center in Mexico.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  13. Plasma miRNA-146b-3p, -222-3p, -221-5p, -21a-3p Expression Levels andInternational journal of molecular sciences · 2024
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  18. The Role ofJournal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabio MedasDepartment of Surgical Sciences, University of Cagliari, 09042 Cagliari, Italy. fabiomedas@gmail.com.
Gian Luigi CanuDepartment of Surgical Sciences, University of Cagliari, 09042 Cagliari, Italy.
Francesco BoiDepartment of Medical Sciences, University of Cagliari, 09042 Cagliari, Italy.
Maria Letizia LaiDivision of Pathological, University of Cagliari AOU, 09127 Cagliari, Italy.
Enrico ErdasDepartment of Surgical Sciences, University of Cagliari, 09042 Cagliari, Italy.
Pietro Giorgio CalòDepartment of Surgical Sciences, University of Cagliari, 09042 Cagliari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differentiated thyroid carcinoma (DTC) is usually associated with a favorable prognosis. Nevertheless, up to 30% of patients present a local or distant recurrence. The aim of this study was to assess the incidence of recurrence after surgery for DTC and to identify predictive factors of recurrence. We included in this retrospective study 579 consecutive patients who underwent thyroidectomy for DTC from 2011 to 2016 at our institution. We observed biochemical or structural recurrent disease in 36 (6.2%) patients; five-year disease-free survival was 94.1%. On univariate analysis, male sex, histotype, lymph node yield, lymph node metastasis, extrathyroidal invasion and multicentricity were associated with significantly higher risk of recurrence, while microcarcinoma was correlated with significantly lower risk of recurrence. On multivariate analysis, only lymph node metastases (OR 4.724,

Indexed as

differentiated thyroid carcinomalymph node metastasismicrocarcinomarecurrent carcinoma

Identifiers

PMID31443531
PMCPMC6770388

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.