Evidence map›Paper›PMID 31443434›Full record

ArticleCells2019

Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition.

Yong Dong, Chengxiang Xia, Qitong Weng, Tongjie Wang, Fangxiao Hu, Kaitao Wang, Xiaofei Liu, Yang Geng, Lijuan Liu, Hongling Wu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yong DongKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Chengxiang XiaKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.ORCID 0000-0002-7923-2802
Qitong WengKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Tongjie WangKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Fangxiao HuKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Kaitao WangJoint School of Life Sciences, Guangzhou Medical University, Guangzhou 510530, China.
Xiaofei LiuKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Yang GengKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Lijuan LiuKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Hongling WuKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China.
Juan DuKey Laboratory of Regenerative Biology of Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou 510530, China. du_juan@gibh.ac.cn.ORCID 0000-0003-4701-3573
Chinese Academy of Sciences · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural hematopoietic stem cells (HSC) are susceptible and tend to lose stemness, differentiate, or die on culture condition in vitro, which adds technical challenge for maintaining

Indexed as

AnimalsCells, CulturedCulture MediaHematopoietic Stem CellsHomeodomain ProteinsMiceMice, Inbred C57BLMice, TransgenicMonomeric GTP-Binding ProteinsMutationNuclear Pore Complex ProteinsCulture MediaHomeodomain ProteinsMonomeric GTP-Binding ProteinsNras protein, mousenuclear pore complex protein 98Nuclear Pore Complex Proteinshematopoietic stem cellsNrasG12DNUP98-HOXA10HD

Identifiers

PMID31443434
PMCPMC6770072
OpenAlexW2969218904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.