Evidence map›Paper›PMID 31443404›Full record

ArticleMolecules (Basel, Switzerland)2019

Next Generation Sequencing-Based Transcriptome Predicts Bevacizumab Efficacy in Combination with Temozolomide in Glioblastoma.

Alimu Adilijiang, Masaki Hirano, Yusuke Okuno, Kosuke Aoki, Fumiharu Ohka, Sachi Maeda, Kuniaki Tanahashi, Kazuya Motomura, Hiroyuki Shimizu, Junya Yamaguchi and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Pharmacogenomics and personalized medicine · 2022
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Alimu AdilijiangDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Masaki HiranoDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Yusuke OkunoCenter for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya 4668560, Japan.
Kosuke AokiDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Fumiharu OhkaDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Sachi MaedaDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Kuniaki TanahashiDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Kazuya MotomuraDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Hiroyuki ShimizuDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Junya YamaguchiDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Toshihiko WakabayashiDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan.
Atsushi NatsumeDepartment of Neurosurgery, Nagoya University School of Medicine, Nagoya 4668550, Japan. anatsume@med.nagoya-u.ac.jp.
Nagoya University · JPNagoya University Hospital · JP

Funding

Japan Society for the Promotion of Science 17928985
6 · The paper itself

Abstract

Glioblastoma (GBM), the most common and malignant brain tumor, is classified according to its

Indexed as

Gene Expression ProfilingTranscriptomeAnimalsAntineoplastic Combined Chemotherapy ProtocolsBevacizumabCell CycleCell SurvivalComputational BiologyDisease Models, AnimalGene Expression Regulation, NeoplasticGene OntologyGlioblastomaHumansIsocitrate DehydrogenaseMiceMutationBevacizumabIDH1 protein, humanIsocitrate DehydrogenaseTemozolomidebevacizumabglioblastomaGO analysisGSEAIDH1 mutationNGSRNA-seqtemozolomideU87 cell line

Identifiers

PMID31443404
PMCPMC6749405
OpenAlexW2969971608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.