Evidence map›Paper›PMID 31443246›Full record

ArticleCancers2019

Hyperthermia Treatment Planning Including Convective Flow in Cerebrospinal Fluid for Brain Tumour Hyperthermia Treatment Using a Novel Dedicated Paediatric Brain Applicator.

Gerben Schooneveldt, Hana Dobšíček Trefná, Mikael Persson, Theo M de Reijke, Klas Blomgren, H Petra Kok, Hans Crezee

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Automatic specific absorption rate (SAR) prediction for hyperthermia treatment planning using deep learning method.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2025
    Article
  4. Article
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Hyperthermia treatment advances for brain tumors.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020
    Review
  13. Article
  14. Heating technology for malignant tumors: a review.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Gerben SchooneveldtDepartment of Radiotherapy, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands. g.schooneveldt@amsterdamumc.nl.
Hana Dobšíček TrefnáDepartment of Electrical Engineering, Chalmers University of Technology, 41296 Gothenburg, Sweden.
Mikael PerssonDepartment of Electrical Engineering, Chalmers University of Technology, 41296 Gothenburg, Sweden.
Theo M de ReijkeDepartment of Urology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Klas BlomgrenDepartment of Women's and Children's Health, Karolinska Institutet, 17164 Stockholm, Sweden.ORCID 0000-0002-0476-7271
H Petra KokDepartment of Radiotherapy, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Hans CrezeeDepartment of Radiotherapy, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-7474-0533
Amsterdam University Medical Centers · NLChalmers University of Technology · SEKarolinska University Hospital · SE

Funding

Barncancerfonden MT2014-0005European Cooperation in Science and Technology ECOST-STSM-BM1309-110117-081725KWF Kankerbestrijding UVA 2012-5539
6 · The paper itself

Abstract

Hyperthermia therapy (40-44 °C) is a promising option to increase efficacy of radiotherapy/chemotherapy for brain tumours, in particular paediatric brain tumours. The Chalmers Hyperthermia Helmet is developed for this purpose. Hyperthermia treatment planning is required for treatment optimisation, but current planning systems do not involve a physically correct model of cerebrospinal fluid (CSF). This study investigates the necessity of fluid modelling for treatment planning. We made treatments plans using the Helmet for both pre-operative and post-operative cases, comparing temperature distributions predicted with three CSF models: a convective "fluid" model, a non-convective "solid" CSF model, and CSF models with increased effective thermal conductivity ("high-

Indexed as

brain malignanciescerebrospinal fluidcomputational fluid dynamicshyperthermia treatmentmedulloblastomatreatment planning

Identifiers

PMID31443246
PMCPMC6721488
OpenAlexW2967427568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.