Evidence map›Paper›PMID 31443159›Full record

ArticleInternational journal of molecular sciences2019

Transcriptional Response of Subcutaneous White Adipose Tissue to Acute Cold Exposure in Mice.

Xiaojuan Liang, Jianfei Pan, Chunwei Cao, Lilan Zhang, Ying Zhao, Yiping Fan, Kui Li, Cong Tao, Yanfang Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaojuan LiangState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.
Jianfei PanState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.
Chunwei CaoState Key Laboratory of Stem Cell and Reproductive Biology, Chinese Academy of Sciences, 100101 Beijing, China.
Lilan ZhangState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.
Ying ZhaoState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.
Yiping FanState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.
Kui LiState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China.
Cong TaoState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China. taocong@caas.cn.
Yanfang WangState Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, 100193 Beijing, China. wangyanfang@caas.cn.
Chinese Academy of Agricultural Sciences · CNChinese Academy of Sciences · CN

Funding

National Natural Science Foundation of China 31601929,31672387
6 · The paper itself

Abstract

Beige adipose tissue has been considered to have potential applications in combating obesity and its related metabolic diseases. However, the mechanisms of acute cold-stimulated beige formation still remain largely unknown. Here, transcriptional analysis of acute cold-stimulated (4 °C for 4 h) subcutaneous white adipose tissue (sWAT) was conducted to determine the molecular signatures that might be involved in beige formation. Histological analysis confirmed the appearance of beige adipocytes in acute cold-treated sWAT. The RNA-sequencing data revealed that 714 genes were differentially expressed (

Indexed as

3T3-L1 CellsAdipocytes, BeigeAdipose Tissue, WhiteAnimalsCold TemperatureMaleMiceMice, Inbred C57BLPeroxisome Proliferator-Activated ReceptorsReal-Time Polymerase Chain ReactionSubcutaneous TissuePeroxisome Proliferator-Activated Receptorsacute cold stimulationbeige adipocytemicetranscriptional analysis

Identifiers

PMID31443159
PMCPMC6720191
OpenAlexW2968964939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.