Evidence map›Paper›PMID 31442406›Full record

ArticleCell2019

Effector T

Maria Carolina Amezcua Vesely, Paris Pallis, Piotr Bielecki, Jun Siong Low, Jun Zhao, Christian C D Harman, Lina Kroehling, Ruaidhrí Jackson, Will Bailis, Paula Licona-Limón and 12 more

Abstract read
In one paragraph

Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 171 citations in OpenAlex.

  1. Single-Cell Profiling Identifies Skin-Resident Memory CD4European journal of immunology · 2026
    Article
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  5. Review
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  7. Article
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  11. Review
  12. Article
  13. AFrontiers in tuberculosis · 2026
    Article
  14. Article
  15. Article
  16. TScience immunology · 2025
    Article
  17. Review
  18. Article
  19. CD4Immunology and cell biology · 2025
    Review
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 5 countries.

Maria Carolina Amezcua VeselyDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, USA.
Paris PallisDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Piotr BieleckiDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Jun Siong LowDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Jun ZhaoDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Department of Pathology, Yale School of Medicine, New Haven, CT 06510, USA; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.
Christian C D HarmanDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, USA.
Lina KroehlingDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Ruaidhrí JacksonDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Will BailisDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Paula Licona-LimónDepartamento de Biología Celular y del Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad de México, México.
Hao XuDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Norifumi IijimaDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Padmini S PillaiDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Koch Institute for Integrative Cancer Research and Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
Daniel H KaplanDepartment of Dermatology and Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Casey T WeaverDepartments of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Yuval KlugerDepartment of Pathology, Yale School of Medicine, New Haven, CT 06510, USA; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Applied Mathematics Program, Yale University, New Haven, CT 06511, USA.
Monika S KowalczykBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Akiko IwasakiDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, USA.
Joao P PereiraDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA.
Enric EspluguesDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Laboratory of Molecular and Cellular Immunology, Principe Felipe Research Center (CIPF), 46012 Valencia, Spain.
Nicola GaglianiDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; I. Medical Department and Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf 20246 Hamburg, Germany; Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institute, 17176 Stockholm, Sweden. Electronic address: n.gagliani@uke.de.
Richard A FlavellDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, USA. Electronic address: richard.flavell@yale.edu.
Yale University · USHoward Hughes Medical Institute · USApplied Mathematics (United States) · USBroad Institute · USCentro de Investigacion Principe Felipe · ESKarolinska Institutet · SEMassachusetts Institute of Technology · USUniversidad Nacional Autónoma de México · MXUniversity of Alabama at Birmingham · USUniversity of Pittsburgh · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Cellular and molecular analysis of B lymphocyte development and selectionR01AI113040 · NIAID · YALE UNIVERSITY · PI JOAO PEREIRA · 2014 to 2026
$6.0M
Regulated Activation of Latent-TGFb Determines Leukocyte Occupancy of the Epidermal NicheR01AR060744 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, DANIEL H · 2011 to 2020
$4.0M
B cell based protection against recurrent herpesR01AI127429 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2017 to 2021
$2.1M
EFFICIENT METHODS FOR CALIBRATION, CLUSTERING, VISUALIZATION AND IMPUTATION OF LARGE scRNA-seq DATAR01GM131642 · NIGMS · YALE UNIVERSITY · PI KLUGER, YUVAL · 2019 to 2022
$1.6M
Th17 Pathway Plasticity in the Pathogenesis of Inflammatory Bowel DiseaseR01DK103744 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WEAVER, CASEY T · 2015 to 2018
$1.3M
EFFICIENT SPECTRAL APPROACHES FOR FINDING UNDERLYING STRUCTURES IN BIG DATAR01HG008383 · NHGRI · YALE UNIVERSITY · PI KLUGER, YUVAL · 2016 to 2018
$1.2M
Howard Hughes Medical InstituteNCATS NIH HHS UL1 TR001863NHGRI NIH HHS R01 HG008383NIAID NIH HHS R01 AI113040NIAID NIH HHS R01 AI127429NIAMS NIH HHS R01 AR060744NIDDK NIH HHS R01 DK103744NIGMS NIH HHS R01 GM131642
6 · The paper itself

Abstract

Adaptive immunity provides life-long protection by generating central and effector memory T cells and the most recently described tissue resident memory T (T

Indexed as

AnimalsCD4-Positive T-LymphocytesDiphtheria ToxinDisease Models, AnimalFemaleImmunologic MemoryInterleukin-17Klebsiella InfectionsKlebsiella pneumoniaeLungMiceMice, Inbred C57BLTh17 CellsDiphtheria ToxinInterleukin-17exT(H)17Fate mappingIL-17IL-7T(H)17Tissue resident memory CD4 T cells

Identifiers

PMID31442406
PMCPMC7057720
OpenAlexW2969302025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.