ArticleProteins2019
Target highlights in CASP13: Experimental target structures through the eyes of their authors.
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In one paragraph
Article in Proteins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
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- Crystal Structure of α-Xylosidase fromACS sustainable chemistry & engineering · 2020Article
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- Target highlights in CASP13: Experimental target structures through the eyes of their authors.Proteins · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
35 authors at 20 institutions in 8 countries.
Rosalba LeporeBSC-CNS Barcelona Supercomputing Center, Barcelona, Spain.ORCID 0000-0002-9481-2557
Andriy KryshtafovychGenome Center, University of California, Davis, California.ORCID 0000-0001-5066-7178
Markus AlahuhtaBiosciences Center, National Renewable Energy Laboratory, Golden, Colorado.
Harshul A VerasztoDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, Germany.
Yannick J BombleBiosciences Center, National Renewable Energy Laboratory, Golden, Colorado.
Joshua C BuftonNuffield Department of Medicine; Structural Genomics Consortium, University of Oxford, Oxford, UK.
Alex N BullockNuffield Department of Medicine; Structural Genomics Consortium, University of Oxford, Oxford, UK.
Cody CabaDepartment of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario, Canada.
Hongnan CaoDepartment of BioSciences, Rice University, Houston, Texas.
Owen R DaviesInstitute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Ambroise DesfossesSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
Matthew DunneInstitute of Food, Nutrition and Health, Zurich, Switzerland.
Krzysztof FidelisGenome Center, University of California, Davis, California.ORCID 0000-0002-8061-412X
Celia W GouldingDepartment of Molecular Biology and Biochemistry; Pharmaceutical Sciences, University of California Irvine, Irvine, California.
Manickam GurusaranInstitute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Irina GutscheInstitut de Biologie Structurale, Université Grenoble Alpes, CEA, CNRS, Grenoble, France.
Christopher J HardingSchool of Biosciences, University of Birmingham, Birmingham, UK.
Marcus D HartmannDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, Germany.
Christopher S HayesDepartment of Molecular, Cellular and Developmental Biology, Biomolecular Science and Engineering Program, University of California, Santa Barbara, California.ORCID 0000-0002-2216-6445
Andrzej JoachimiakStructural Biology Center, Biosciences Division, Midwest Center for Structural Genomics, Argonne.
Petr G LeimanDepartment of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, Texas.
Peter LoppnauStructural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.
Andrew L LoveringSchool of Biosciences, University of Birmingham, Birmingham, UK.
Vladimir V LuninBiosciences Center, National Renewable Energy Laboratory, Golden, Colorado.
Karolina MichalskaStructural Biology Center, Biosciences Division, Midwest Center for Structural Genomics, Argonne.
Ignacio Mir-SanchisDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois.
A K MitraSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
John MoultInstitute for Bioscience and Biotechnology Research, Department of Cell Biology and Molecular genetics, University of Maryland, Rockville, Maryland, USA.
George N PhillipsDepartment of BioSciences, Rice University, Houston, Texas.
Daniel M PinkasNuffield Department of Medicine; Structural Genomics Consortium, University of Oxford, Oxford, UK.
Phoebe A RiceDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois.
Yufeng TongDepartment of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario, Canada.
Maya TopfInstitute of Structural and Molecular Biology, Birkbeck, University College London, London, UK.
Jonathan D WaltonGreat Lakes Bioenergy Research Center and Department of Plant Biology, Michigan State University, East Lansing, Michigan.
Torsten SchwedeBiozentrum University of Basel, Basel, Switzerland.ORCID 0000-0003-2715-335X
National Laboratory of the Rockies · USUniversity of Illinois Chicago · USCentre National de la Recherche Scientifique · FRMax Planck Institute for Developmental Biology · DENewcastle University · GBUniversity of Birmingham · GBUniversity of California, Davis · USUniversity of Oxford · GBUniversity of Toronto · CAUniversity of Wisconsin–Madison · USBarcelona Supercomputing Center · ESDepartment of Health Canton of Zurich · CHGreat Lakes Bioenergy Research Center · USInstitute of Structural and Molecular Biology · GBJoint Center for Structural Genomics · USSIB Swiss Institute of Bioinformatics · CHThe University of Texas Medical Branch at Galveston · USUniversity of Auckland · NZUniversity of Bristol · GBUniversity of California, Irvine · US
Funding
Midwest Center for Structural GenomicsU54GM094585 · NIGMS · UNIVERSITY OF CHICAGO · PI THORNTON, JANET · 2010 to 2014
$33.7MProspective analysis to determine model accuracy performance and boundaries in the post-AlphaFold2 environmentR01GM100482 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIDELIS, KRZYSZTOF A · 2012 to 2025
$11.1MThe Midwest Center for Structural Genomics - Community ResourceR24GM115586 · NIGMS · UNIVERSITY OF CHICAGO · PI JOACHIMIAK, ANDRZEJ · 2015 to 2017
$2.8MEnzyme Discovery for Natural Product BiosynthesisU01GM098248 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PHILLIPS, GEORGE NEAL · 2011 to 2015
$2.8MStructure-function analysis of polymorphic CDI toxin-immunity protein complexes aU01GM102318 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GOULDING, CELIA · 2012 to 2016
$1.7MLifestyle of the SCCmec element and mechanisms of self-loading helicasesR01GM121655 · NIGMS · UNIVERSITY OF CHICAGO · PI RICE, PHOEBE A · 2017 to 2020
$1.7MMolecular mechanisms of antibacterial CDI toxin activationR01GM117373 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOULDING, CELIA, HAYES, CHRISTOPHER S. · 2016 to 2019
$1.2MBiotechnology and Biological Sciences Research Council 1500753NIGMS NIH HHS GM100482NIGMS NIH HHS R01 GM100482NIGMS NIH HHS R01 GM117373NIGMS NIH HHS R01 GM121655NIGMS NIH HHS R24 GM115586NIGMS NIH HHS U01 GM098248NIGMS NIH HHS U01 GM102318NIGMS NIH HHS U54 GM094585NIH HHS GM094585NIH HHS GM098248NIH HHS GM102318NIH HHS GM115586NIH HHS GM117373Wellcome TrustWellcome Trust 104158/Z/14/ZWellcome Trust 106169/ZZ14/ZWellcome Trust RG170118
Abstract
The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.
Indexed as
Computational BiologyProtein ConformationArabidopsisBacterial ProteinsCrystallography, X-RayHumansModels, MolecularProteinsBacterial ProteinsProteinsCASP, protein structure predictioncryo-EMX-ray crystallography
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.