ArticleMedicine2019
Intermittent alien hand syndrome caused by Marchiafava-Bignami disease: A case report.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Unraveling the mystery of alien hand syndrome: when your hand has a mind of its own.Orphanet journal of rare diseases · 2025Review
- Alien Hand: Current Research Trends.Current neurology and neuroscience reports · 2025Review
- Late Detection of Corpus Callosum Infarction in a 55-Year-Old: Insights from Alien Hand Syndrome.The American journal of case reports · 2025Article
- Clinical analysis of Marchiafava-Bignami disease.BMC neurology · 2024Article
- Marchiafava Bignami Disease: A Rare Neurological Complication of Long-Term Alcohol Abuse.Cureus · 2022Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleAlien Hand syndrome (AHS) is characterized in most patients by seemingly purposeful, involuntary movements of the extremities. It is not well known among physicians on account of its diverse clinical manifestations. PATIENT CONCERNS: We present a 57-year-old Chinese man who could not stop or turn himself around as he involuntarily and uncontrollably walked forward, which had happened frequently in the month prior to treatment. He had been a heavy drinker for thirty years before the onset of the disease, with an alcohol intake of 600 to 800 ml/day. DIAGNOSES: History of alcohol intake and the brain magnetic resonance imaging findings indicated a diagnosis of Marchiafava-Bignami disease. The patient was additionally diagnosed with Alien Hand Syndrome according to his clinical symptoms.
interventionsThe patient was treated with high doses of vitamin B for 1 month. OUTCOMES: The patient's abnormal behaviors never appeared during the treatment, and no instance of recurrence was observed during the 6 months of follow-up. LESSONS: The clinical manifestation of AHS is non-specific. Only by considering its diverse manifestation can doctors better understand the disease and achieve early intervention.
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Registered trials
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