Evidence map›Paper›PMID 31441428›Full record

ArticleEmerging infectious diseases2019

Classification of Trauma-Associated Invasive Fungal Infections to Support Wound Treatment Decisions.

Anuradha Ganesan, Faraz Shaikh, William Bradley, Dana M Blyth, Denise Bennett, Joseph L Petfield, M Leigh Carson, Justin M Wells, David R Tribble, Infectious Disease Clinical Research Program Trauma Infectious Disease Outcomes Study Group

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Mucormycosis.Infectious disease clinics of North America · 2025
    Review
  5. Article
  6. Epidemiology and timing of infectious complications from battlefield-related burn injuries.Burns : journal of the International Society for Burn Injuries · 2024
    Article
  7. Review
  8. Article
  9. Deep Sternal Wound Infection Caused byOpen forum infectious diseases · 2024
    Article
  10. A Lateral-Flow Device for the Rapid Detection ofDiagnostics (Basel, Switzerland) · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Combat trauma-related invasive fungal wound infections.Current fungal infection reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anuradha Ganesan
Faraz Shaikh
William Bradley
Dana M Blyth
Denise Bennett
Joseph L Petfield
M Leigh Carson
Justin M Wells
David R Tribble
Infectious Disease Clinical Research Program Trauma Infectious Disease Outcomes Study Group

Funding

DATA CENTER FOR EPIDEMIOLOGIC INVESTIGATIONS OF HIVN01AI005072 · NIAID · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, SONJA M · 1990 to 1994
–
NIAID NIH HHS Y01 AI005072
6 · The paper itself

Abstract

To evaluate a classification system to support clinical decisions for treatment of contaminated deep wounds at risk for an invasive fungal infection (IFI), we studied 246 US service members (413 wounds) injured in Afghanistan (2009-2014) who had laboratory evidence of fungal infection. A total of 143 wounds with persistent necrosis and laboratory evidence were classified as IFI; 120 wounds not meeting IFI criteria were classified as high suspicion (patients had localized infection signs/symptoms and had received antifungal medication for >10 days), and 150 were classified as low suspicion (failed to meet these criteria). IFI patients received more blood than other patients and had more severe injuries than patients in the low-suspicion group. Fungi of the order Mucorales were more frequently isolated from IFI (39%) and high-suspicion (21%) wounds than from low-suspicion (9%) wounds. Wounds that did not require immediate antifungal therapy lacked necrosis and localized signs/symptoms of infection and contained fungi from orders other than Mucorales.

Indexed as

Decision Support Systems, ClinicalMilitary PersonnelMultiple TraumaAfghan Campaign 2001-AspergillusFusariumHumansInvasive Fungal InfectionsMucoralesUnited StatesWound InfectionAfghanistanbacteriablast woundfungiinvasive fungal infectionsmucormycosistraumawound infection

Identifiers

PMID31441428
PMCPMC6711217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.