Evidence map›Paper›PMID 31441374›Full record

ArticleJournal of neurotrauma2020

Neuron-Derived Plasma Exosome Proteins after Remote Traumatic Brain Injury.

Edward J Goetzl, Carrie B Peltz, Maja Mustapic, Dimitrios Kapogiannis, Kristine Yaffe

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

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  19. AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting NaAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Edward J GoetzlDepartment of Medicine, University of California, San Francisco, San Francisco, California.
Carrie B PeltzSan Francisco VA Medical Center, San Francisco, California.
Maja MustapicIntramural Research Program, National Institute on Aging, Baltimore, Maryland.
Dimitrios KapogiannisIntramural Research Program, National Institute on Aging, Baltimore, Maryland.
Kristine YaffeDepartment of Neurology-Psychiatry, University of California, San Francisco, San Francisco, California.
National Institute on Aging · USSan Francisco VA Medical Center · USUniversity of California, San Francisco · US

Funding

Studies in Dementia and Neurodegenerative DiseasesZIAAG000975 · NIA · NATIONAL INSTITUTE ON AGING · PI KAPOGIANNIS, DIMITRIOS · 2009 to 2025
$31.5M
6 · The paper itself

Abstract

To identify long-term effects of traumatic brain injury (TBI) on levels of plasma neuron-derived exosome (NDE) protein biomarkers of cognitive impairment (CI), plasmas were obtained from four groups of older veterans, who were matched for age and sex: no TBI or CI (

Indexed as

AgedAged, 80 and overBiomarkersBrain Injuries, TraumaticCognitive DysfunctionExosomesFemaleHumansMaleMiddle AgedNeuronsBiomarkersamyloidbiomarkersphospho-tauprion cellular proteinproteinopathic neurodegenerationsynaptogyrin-3

Identifiers

PMID31441374
PMCPMC6964810
OpenAlexW2969603351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.