Evidence map›Paper›PMID 31441300›Full record

ArticleThe Journal of organic chemistry2019

Identifying Amidyl Radicals for Intermolecular C-H Functionalizations.

Matthew M Tierney, Stefano Crespi, Davide Ravelli, Erik J Alexanian

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Functionalization of strong C(spChemical science · 2026
    Article
  2. Article
  3. Aminoalkylation of Alkenes Enabled by Triple Radical Sorting.Journal of the American Chemical Society · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Electrophilic Aminating Agents in Total Synthesis.Angewandte Chemie (International ed. in English) · 2021
    Review
  9. Journal of the American Chemical Society · 2021
    Article
  10. Site Selective Chlorination of C(spAngewandte Chemie (International ed. in English) · 2021
    Article
  11. Practical and Selective spAngewandte Chemie (International ed. in English) · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew M TierneyDepartment of Chemistry , The University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
Stefano CrespiPhotoGreen Lab, Department of Chemistry , University of Pavia , viale Taramelli 12 , 27100 Pavia , Italy.ORCID 0000-0002-0279-4903
Davide RavelliPhotoGreen Lab, Department of Chemistry , University of Pavia , viale Taramelli 12 , 27100 Pavia , Italy.ORCID 0000-0003-2201-4828
Erik J AlexanianDepartment of Chemistry , The University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.ORCID 0000-0002-0256-2133

Funding

Intermolecular Aliphatic C-H Functionalization Using Heteroatom-Centered RadicalsR01GM120163 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALEXANIAN, ERIK JOHN · 2016 to 2019
$971k
NIGMS NIH HHS R01 GM120163
6 · The paper itself

Abstract

Recent studies have demonstrated the capabilities of amidyl radicals to facilitate a range of intermolecular functionalizations of unactivated, aliphatic C-H bonds. Relatively little information is known regarding the important structural and electronic features of amidyl and related radicals that impart efficient reactivity. Herein, we evaluate a diverse range of nitrogen-centered radicals in unactivated, aliphatic C-H chlorinations. These studies establish the salient features of nitrogen-centered radicals critical to these reactions in order to expedite the future development of new site-selective, intermolecular C-H functionalizations.

Indexed as

AmidesFree RadicalsMolecular StructureAmidesFree Radicals

Identifiers

PMID31441300
PMCPMC6834340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.